Description
Book SynopsisExplains and surveys one of the most exciting areas of oral biology research Demonstrates the clinical relevance and practical application of saliva diagnostics Inter-disciplinary relevance and appeal across industry and academia Written by luminary team headed by one of the world's recognized authorities in the field.
Table of ContentsContributors viii
Foreword xv
Preface xvii
Acknowledgment xviii
I Background and Foundation
1 Salivary Gland Development and Regeneration 3
Sarah M. Knox and Matthew P. Hoffman
2 Salivary Gland Physiology Relevant to Diagnostics 14
Victor G. Romanenko and James E. Melvin
3 Saliva: Properties and Functions 27
Arie van Nieuw Amerongen, Enno C.I. Veerman, and Arjan Vissink
4 Saliva Collectors 37
Arjan Vissink, Andy Wolff, and Enno C.I. Veerman
5 Salivary Secretion in Health and Disease 60
Michael D. Turner and Jonathan A. Ship
6 Processing and Storage of Saliva Samples 69
Enno C.I. Veerman, Arjan Vissink, David T. Wong, and Arie van Nieuw Amerongen
II Saliva Diagnostics
7 Historical Perspectives and Present 79
Frank G. Oppenheim
8 Diagnostics Other Than Blood 94
Sudhir Srivastava and Karl Krueger
9 Perceptions of Saliva: Relevance to Clinical Diagnostics 104
Sreenivas Koka and David T. Wong
10 Saliva-Based Diagnostic Technologies: Highlights of the NIDCR's Program 111
Eleni Kousvelari, John T. McDevitt, Daniel Malamud, David T. Wong, and David R. Walt
11 Human Salivary Proteomics 122
Shen Hu, Markus Hardt, Susan J. Fisher, David T. Wong, John R. Yates, James E. Melvin, and Joseph A. Loo
12 Genomic Targets in Saliva 129
Bernhard G. Zimmermann, Zhanzhi Hu, and David T. Wong
13 Point-of-Care Diagnostics for Infectious diseases 136
Paul L.A.M. Corstjens, Daniel Malamud
14 Dental Caries Risk Assessment 150
Paul C. Denny and Patricia A. Denny
15 Periodontal Disease 156
Christoph A. Ramseier, Thiago Morelli, Janet S. Kinney, Meghan Dubois, Lindsay Rayburn, and William Giannobile
16 Role of Saliva in Detection of Substance Abuse 169
Uttam Garg and Lance Presley
17 Head and Neck Cancer 180
Joseph A. Califano and Suhail K. Mithani
18 Sjogren's Syndrome 189
Philip C. Fox
19 Salivary Gland Dysfunction Associated with Systemic Disease 198
Nelson L. Rhodus
20 Progression and Treatment Evaluation in Diseases Affecting Salivary Glands 214
Jiska M. Meijer, Cees G.M. Kallenberg, and Arjan Vissink
21 The Uses of Saliva in Forensic Genetics 226
Jack Ballantyne and Jane Juusola
22 SPKB—Salivary Proteome Knowledge Base: A Platform for Collaborative Proteomics Research 233
Weihong Yan, Weixia Yu, Shawn Than, Renli Qiao, D. Stott Parker, Joseph A. Loo, and David T. Wong
III Saliva Diagnostics—A New Industry
23 Commercialization of Oral Fluid Products and Technologies 243
R. Sam Niedbala
24 Coverage and Reimbursement for Salivary Diagnostic Tests 255
James J. Crall
25 Saliva Diagnostics in the Dentist's and Physician's Office 263
Chakwan Siew and Milton V. Marshall
26 Salivary Hormones in Research and Diagnostics 270
Douglas A. Granger, Christine K. Fortunato, Leah C. Hibel
27 Crossroads Between Saliva Diagnostics and Salivary Gland Gene Therapy 278
Bruce J. Baum, Ana P. Cotrim, Corinne M. Goldsmith, Fumi Mineshiba, Senrong Qi, Gabor Z. Racz, Yuval Samuni, Takayuki Sugito, Antonis Voutetakis, and Changyu Zheng
28 Saliva Diagnostics—A New Industry 288
Stuart R. Smith, David T. Wong, and R. Michael Buch
Index 295
