Description
Book SynopsisQuantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This advanced-level textbook covers all the statistical methods that have been used or proposed for detection and analysis of QTL and marker- and gene- assisted selection in animal genetics and breeding, as well as new advances that have revolutionized the field since the first edition.
Trade Review"...the book is certainly a must-have for anyone involved in the statistical analysis of QTL studies in livestock... and (is) a useful textbook for advanced undergraduate and postgraduate students" - Chris Haley, Roslin Institute, on the first edition."
Table of Contents1: Principles of Parameter Estimation 2: Random and Fixed Effects, the Mixed Model 3: Historical Overview 4: Experimental Designs to Detect QTL, Generation of Linkage Disequilibrium 5: QTL Parameter Estimation for Crosses between Inbred Lines 6: Advanced Statistical Methods for QTL Detection and Parameter Estimation 7: Analysis of QTL as Random Effects 8: Statistical Power to Detect QTL, and Parameter Confidence Intervals 9: Optimization of Experimental Designs 10: Fine Mapping of QTL 11: Complete Genome QTL Scans: The Problem of Multiple Comparisons 12: Multiple Trait QTL Analysis 13: Principles of Selection Index and Traditional Breeding Programmes 14: Marker-assisted Selection:Theory 15: Marker-assisted Selection : Results of Simulation Studies 16: Marker-assisted Introgression
