Description
Book SynopsisThis volume looks at classic and novel methods currently used by researchers to understand mood and anxiety disorders and foster precision medicine. Chapters in this book cover topics such as how the sucrose preference succeeds or fails as a measurement of anhedonia; fear conditioning in laboratory rodents; animal models for mania; rodent models for studying the impact of variation in early life mother-infant interactions on mood and anxiety; and prediction of susceptibility/resilience toward animal models of PTSD. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Comprehensive and cutting-edge, accommodating the novel views on how the neurobiology of psychiatric disorders should be reconceptualized, Psychiatric Vulnerability, Mood, and Anxiety Disorders: Tests and Models in Mice and Rats is a valuable resource for all researchers i
Table of Contents
1 Animal Models of Mood and Anxiety Disorders: The Pursuit of Standardization and Recognition of the Complex Neurobiology of Human Mental Health
Jaanus Harro
2 The Open Field Test
Vootele Võikar and S. Clare Stanford
3 The Light Dark Box Test in the Mouse
Solal Bloch and Catherine Belzung
4 The Olfactory Bulbectomized Rodent Remains a Valuable Preclinical Model of Depression and Antidepressant Activity
Michelle Roche and John P. Kelly
5 Marble-Burying in Mice
Jeffrey M. Witkin and Jodi L. Smith
6 How the Sucrose Preference Succeeds or Fails as a Measurement of Anhedonia
Tatyana Strekalova
7 A Vogel Conflict Test Using Food Reinforcement in Mice
Jeffrey M. Witkin and Jodi L. Smith
8 Fear Conditioning in Laboratory Rodents
Iris Müller and Markus Fendt
9 Learned Helplessness in Rodents
Kennia Moura Silveira and Sâmia Joca
10 Chronobiology of Mood States: Introducing Circadian Animal Models
Jorge Mendoza, Noëmi Billon, Guillaume Vanotti, and Viviane Pallage
11 Telemetry in Rats and Mice: Methodological Considerations and Example Studies of Stress and Anxiety in Ground-Based Spaceflight Analogs
Laurie L. Wellman, Austin M. Adkins, Hargsoon Yoon, Richard A. Britten, and Larry D. Sanford
12 Utility and Implementation of Oral Corticosteroid Exposure in Behavioral Neuroscience Research with Rodents
Michelle K. Sequeira, Jane R. Taylor, and Shannon L. Gourley
13 Animal Models for Mania
Kirsten Schmerder and Nadja Freund
14 Social Behavior Testing in Mice: Social Interest, Recognition, and Aggression
Amy E. Clipperton-Allen and Damon T. Page
15 Rodent Models for Studying the Impact of Variation in Early Life Mother-Infant Interactions on Mood and Anxiety
Hannah E. Lapp and Frances A. Champagne
16 Principles of Recording Rodent Ultrasonic Vocalizations
Stefan M. Brudzynski and Sylvie Granon
17 Development of a Selectively Bred Mouse Model of Dominance and Submissiveness: Technical Considerations
Albert Pinhasov, Elena Shmerkin, Lev Libergod, Michael Kirby, Oryan Agranyoni, Liudmila Vinnikova, and Debpali Sur
18 Prediction of Susceptibility/Resilience Toward Animal Models of Post-Traumatic Stress Disorder (PTSD)
Maria Morena, Giulia Federica Mancini, and Patrizia Campolongo
