Description
Book SynopsisProtein Design: Method and Applications, Second Edition expands upon the previous edition with current, detailed ideas on how to approach a potential protein design project.
Table of Contents1. De novo Design of Stable α-helices
Alexander Yakimov, Georgy Rychkov, and Michael Petukhov
2. Design of Monomeric Water-soluble b-hairpin and β-sheet Peptides
M. Angeles Jiménez
3. Combination of Theoretical and Experimental Approaches for the Design and Study of Fibril-forming Peptides
Phanourios Tamamis, Emmanouil Kasotakis, Georgios Archontis, and Anna Mitraki
4. Posttranslational Incorporation of Non-canonical Amino Acids in the RNase S System by Semisynthetic Protein Assembly
Maika Genz and Norbert Sträter
5. Design, Synthesis, and Study of Fluorinated Proteins
Benjamin C. Buer and E. Neil G. Marsh
6. High-Quality Combinatorial Protein Libraries Using the Binary Patterning Approach
Luke H. Bradley
7. Methods for Library-Scale Computational Protein Design
Lucas B. Johnson, Thaddaus R. Huber, and Christopher D. Snow
8. Symmetric Protein Architecture in Protein Design: Top-Down Symmetric Deconstruction
Liam M. Longo and Michael Blaber
9. Identification of Protein Scaffolds for Enzyme Design using Scaffold Selection
André C. Stiel, Kaspar Feldmeier, and Birte Höcker
10. Computational Design of Novel Enzymes without Cofactors
Matthew D. Smith, Alexandre Zanghellini, and Daniela Grabs
11. De novo Design of Peptide Scaffolds as Novel Pre-organised Ligands for Metal-ion Coordination
Aimee J. Gamble and Anna F. A. Peacock
12. Computational Design of Metalloproteins
Avanish S. Parmar, Douglas Pike, and Vikas Nanda
13. Incorporation of Modified and Artificial Cofactors into Naturally Occurring Protein Scaffolds
Koji Oohor and Takashi Hayashi
14. Computational Redesign of Metalloenzymes for Catalyzing New Reactions
Per Jr. Greisen and Sagar D. Khare
