Description
Book SynopsisThis intriguing study will interest historians of medicine and science, policymakers, and clinicians alike.
Trade ReviewPodolsky's scholarship is awesome, and his grasp of the philosophical and sociologic context of the issues considered make this an important work. New England Journal of Medicine 2006 This thoroughly documented, carefully written book is a landmark analysis... It should be read by everyone who is involved in research and therapeutic development. JAMA 2006 Run; don't walk, to procure your copy of this marvelous book! -- Roni Grad Pharmacy in History 2006 A useful narrative for those with a keen interest in the history of antimicrobial therapy. -- Michael Luchi Journal of the History of Medicine 2008 The book is full of convincing arguments and very sensitive intuitions. It is useful and worthwhile to draw attention, as Podolsky has, to the neglected period of therapeutic culture change between the Golden Age of Microbiology and the advent of antibiotics. -- Christian Bonah Gesnerus 2007 Podolsky thus examines a forgotten or unexplored aspect of medical history [and] his study also throws light on the antibiotic revolution itself. -- Linda Bryder Health and History 2007
Table of ContentsAcknowledgments
Introduction: Patterns of Resistance
Part I: Serotherapy and the Rise of the Specific, 1891-1930
1. The Advent of Type-Specific Antipneumococcal Serotherapy
2. A "Specific" Specific and the Turbid Age of Applied Immunology
3. Fundamental Tensions: Clinical "Proof" and Clinical Resistance
Part II: The Transformation of Pneumonia into a Public Health Concern, 1930-1939
4. The Massachusetts Experiment and New (York) Tensions
5. The New Standard, the New Deal, and the Pneumonia Control Programs
Part II: Resolution: The Antimicrobial "Revolution" and the Decline of Serotherapy, 1939-present
6. Histology of a Revolution
7. A "Modern" Revolution: The Limits and Uses of Controlled Clinical Trials
8. The Dismantling of Pneumonia as a Public Health Concern
Conclusion: Overcoming Resistance
Notes
Index