Description
Book SynopsisPharmacogenomics is the process of analyzing patients' genes to predict the onset of adverse reactions or forecast the effectiveness of therapeutic drugs. This useful text is written to discuss both the theory and the clinical application of the principles of pharmacogenomics.
Trade Review“This book is unique in its focus on the application of pharmacogenomics in clinical therapeutics.” (Doody’s,
19 January 2013)
Table of ContentsList of Contributors, vii
Preface, ix
1 Pharmacogenomics Principles: Introduction to Personalized Medicine, 1
Parvaz Madadi, PhD and Gideon Koren, MD
2 Traditional Therapeutic Drug Monitoring and Pharmacogenomics: Are They Complementary? 15
Christine L.H. Snozek, PhD, Loralie J. Langman, PhD, and Amitava Dasgupta, Ph.D
3 Pharmacogenomics Aspect of Warfarin Therapy, 26
Matthew D. Krasowski, MD, PhD
4 Pharmacogenetics and Cancer Chemotherapy, 39
Christine L.H. Snozek
5 Pharmacogenomic Considerations in Anesthesia and Pain Management, 53
Christine M. Formea, PharmD and Wayne T. Nicholson, MD, PharmD
6 Pharmacogenomics of Immunosuppressants, 70
Nicolas Picard, PharmD, PhD and Pierre Marquet, MD, PhD
7 Pharmacogenomics of Cardiovascular Drugs, 98
Linnea M. Baudhuin, PhD
8 Pharmacogenomic Aspects of Antiretroviral Therapy, 127
Natella Y. Rakhmanina, MD, PhD and John N. van den Anker, MD, PhD
9 Pharmacogenetics of Psychoactive Drugs, 144
Jorge L. Sepulveda, MD, PhD
10 Pharmacogenomic Aspects of Adverse Drug–Drug Interactions, 176
Loralie J. Langman, PhD and Christine L.H. Snozek, PhD
11 Microarray Technology and Other Methods in Pharmacogenomics Testing, 185
Jorge L. Sepulveda, MD, PhD
12 Pharmacogenetic Testing in the Clinical Laboratory Environment, 201
Mark P. Borgman, PhD and Mark W. Linder, PhD
Index, 225
