Description

Book Synopsis
This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics.

Trade Review

“This is a well-written book that I highly recommend to anyone interested in any aspect of personalized medicine.” (Doody’s, 24 August 2012)



Table of Contents

Preface vii

Contributors ix

1. Pharmacogenetics: A Historical Perspective 1
Ann K. Daly

Part I Pharmacogenetics: Relationship to Pharmacokinetics and Pharmacodynamics

2. Pharmacogenetics in Drug Metabolism: Role of Phase I Enzymes 15
Vita Dolžan

3. Pharmacogenetics of Phase II Drug Metabolizing Enzymes 81
Ingolf Cascorbi

4. Pharmacogenetics of Drug Transporters 101
Henriette E. Meyer zu Schwabedissen, Markus Grube, and Heyo K. Kroemer

5. Pharmacogenetics of Drug Targets 149
Ann K. Daly and Maria Arranz

Part II Pharmacogenetics: Therapeutic Areas

6. Cardiovascular Pharmacogenetics 185
Bas J. M. Peters, Anthonius de Boer, Tom Schalekamp, Olaf H. Klungel, and Anke-Hilse Maitland-van der Zee

7. Pharmacogenetics in Psychiatry 215
Evangelia M. Tsapakis, Sarah Curran, Ruth I. Ohlsen, Nora S. Vyas, Katherine J. Aitchison, and Ann K. Daly

8. Pharmacogenetics in Cancer 251
Sharon Marsh

9. Pharmacogenetics of Asthma and COPD 271
Ellen S. Koster, Jan A. M. Raaijmakers, Anke-Hilse Maitland-van der Zee, and Gerard H. Koppelman

10. Pharmacogenetics of Adverse Drug Reactions 295
Ann K. Daly, Martin Armstrong, and Munir Pirmohamed

11. Pharmacogenomics of Inflammatory Bowel Diseases 323
Alexander Teml, Susanne Karner, Elke Schaeffeler, and Matthias Schwab

12. Pharmacogenetics of Pain Medication 353
Jörn Lötsch

Part III Pharmacogenetics: Implementation in Clinical Practice

13. Ethical and Social Issues in Pharmacogenomics Testing 377
Susanne Vijverberg, Toine Pieters, and Martina Cornel

Part IV Developments in Pharmacogenetic Research

14. High-Throughput Genotyping Technologies for Pharmacogenetics 403
Beatriz Sobrino and Angel Carracedo

15. Developments in Analyses in Pharmacogenetic Datasets 415
Alison A. Motsinger-Reif

Part V Pharmacogenetics: Industry and Regulatory Affairs

16. Applications of Pharmacogenetics in Pharmaceutical Research and Development 439
Daniel K. Burns and Scott S. Sundseth

17. Role of Pharmacogenetics in Registration Processes 461
Myong-Jin Kim, Issam Zineh, Shiew-Mei Huang, and Lawrence J. Lesko

Part VI Conclusions

18. Pharmacogenetics: Possibilities and Pitfalls 479
Anke-Hilse Maitland-van der Zee and Ann K. Daly

Index 485

Pharmacogenetics and Individualized Therapy

    Product form

    £98.96

    Includes FREE delivery

    RRP £109.95 – you save £10.99 (9%)

    Order before 4pm tomorrow for delivery by Fri 10 Jul 2026.

    A Hardback by Anke-Hilse Maitland-van der Zee, Ann K. Daly

      Trusted by thousands of customers. See 2,385+ Customer Reviews

      View other formats and editions of Pharmacogenetics and Individualized Therapy by Anke-Hilse Maitland-van der Zee

      Publisher: John Wiley & Sons Inc
      Publication Date: 25/05/2012
      ISBN13: 9780470433546, 978-0470433546
      ISBN10: 047043354X
      Also in:
      Biology, life sciences Chemistry

      Description

      Book Synopsis
      This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics.

      Trade Review

      “This is a well-written book that I highly recommend to anyone interested in any aspect of personalized medicine.” (Doody’s, 24 August 2012)



      Table of Contents

      Preface vii

      Contributors ix

      1. Pharmacogenetics: A Historical Perspective 1
      Ann K. Daly

      Part I Pharmacogenetics: Relationship to Pharmacokinetics and Pharmacodynamics

      2. Pharmacogenetics in Drug Metabolism: Role of Phase I Enzymes 15
      Vita Dolžan

      3. Pharmacogenetics of Phase II Drug Metabolizing Enzymes 81
      Ingolf Cascorbi

      4. Pharmacogenetics of Drug Transporters 101
      Henriette E. Meyer zu Schwabedissen, Markus Grube, and Heyo K. Kroemer

      5. Pharmacogenetics of Drug Targets 149
      Ann K. Daly and Maria Arranz

      Part II Pharmacogenetics: Therapeutic Areas

      6. Cardiovascular Pharmacogenetics 185
      Bas J. M. Peters, Anthonius de Boer, Tom Schalekamp, Olaf H. Klungel, and Anke-Hilse Maitland-van der Zee

      7. Pharmacogenetics in Psychiatry 215
      Evangelia M. Tsapakis, Sarah Curran, Ruth I. Ohlsen, Nora S. Vyas, Katherine J. Aitchison, and Ann K. Daly

      8. Pharmacogenetics in Cancer 251
      Sharon Marsh

      9. Pharmacogenetics of Asthma and COPD 271
      Ellen S. Koster, Jan A. M. Raaijmakers, Anke-Hilse Maitland-van der Zee, and Gerard H. Koppelman

      10. Pharmacogenetics of Adverse Drug Reactions 295
      Ann K. Daly, Martin Armstrong, and Munir Pirmohamed

      11. Pharmacogenomics of Inflammatory Bowel Diseases 323
      Alexander Teml, Susanne Karner, Elke Schaeffeler, and Matthias Schwab

      12. Pharmacogenetics of Pain Medication 353
      Jörn Lötsch

      Part III Pharmacogenetics: Implementation in Clinical Practice

      13. Ethical and Social Issues in Pharmacogenomics Testing 377
      Susanne Vijverberg, Toine Pieters, and Martina Cornel

      Part IV Developments in Pharmacogenetic Research

      14. High-Throughput Genotyping Technologies for Pharmacogenetics 403
      Beatriz Sobrino and Angel Carracedo

      15. Developments in Analyses in Pharmacogenetic Datasets 415
      Alison A. Motsinger-Reif

      Part V Pharmacogenetics: Industry and Regulatory Affairs

      16. Applications of Pharmacogenetics in Pharmaceutical Research and Development 439
      Daniel K. Burns and Scott S. Sundseth

      17. Role of Pharmacogenetics in Registration Processes 461
      Myong-Jin Kim, Issam Zineh, Shiew-Mei Huang, and Lawrence J. Lesko

      Part VI Conclusions

      18. Pharmacogenetics: Possibilities and Pitfalls 479
      Anke-Hilse Maitland-van der Zee and Ann K. Daly

      Index 485

      Recently viewed products

      © 2026 Book Curl

        • American Express
        • Apple Pay
        • Diners Club
        • Discover
        • Google Pay
        • Maestro
        • Mastercard
        • PayPal
        • Shop Pay
        • Union Pay
        • Visa

        Login

        Forgot your password?

        Don't have an account yet?
        Create account