Description
Book SynopsisVolume 76 in the venerable
Organic Reactions series comprises three chapters that cover the ever-increasing emphasis of transition metal catalysis in organic synthesis. These three chapters represent some of the most important transformations that enable the construction of carbon-carbon bonds, heterocycles and carbon-heteratom bonds. This volume features a comprehensive treatment of transition metal (palladium, nickel, copper) catalyzed a-arylation of enolates derived from many common functional groups such as ketones, aldehydes, esters and nitriles (Prim, Marque, Gaucher, Campagne) including enantioselective variants; palladium catalyzed cyclization to form indoles (Cacchi, Fabrizi, Goggiamani) one of the most prevalent and important classes of heterocycles in natural products and pharmaceutical agents; and an overview of a newly developed dihydroxylation reaction of alkenes (Donohoe, Bataille, Innocenti) that uses hydrogen bonding interactions to direct the delivery of an osm
Table of Contents1. HYDROGEN-BONDING-MEDIATED DIRECTED OSMIUM DIHYDROXYLATION
Timothy J. Donohoe, Carole J. R. Bataille, and Paolo Innocenti1
2. TRANSITION-METAL-CATALYZED α-ARYLATION OF ENOLATES
Damien Prim, Sylvain Marque, Anne Gaucher, and Jean-Marc Campagne 49
3. INDOLES VIA PALLADIUM-CATALYZED CYCLIZATION
Sandro Cacchi, Giancarlo Fabrizi, and Antonella Goggiamani 281
CUMULATIVE CHAPTER TITLES BY VOLUME535
AUTHOR INDEX, VOLUMES 1–76 551
CHAPTER AND TOPIC INDEX, VOLUMES 1–76 557
