Description
Book SynopsisThis volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin. The text provides a thorough overview of NSAIDS and aspirin, reviewing such topics as pharmacology and mechanisms, clinical effects, and the safety and efficacy of these drugs. It also focuses on the effect of the drugs on the cardiovascular system and in the prevention of GI cancer. Practical recommendations for a safe prescription of NSAIDs are also included.
Written by experts in the field,
NSAIDs and Aspirin: Recent Advances and Implications for Clinical Management is a comprehensive text of great value to gastroenterologists, rheumatologists, cardiologists, oncologists, orthopedists, trauma and internal medicine specialists.
Trade Review“This well-organized book describes the pharmacology and effects on various organ systems of aspirin and NSAIDS, and guides clinical decision making regarding the use of these medications. … It is appropriate specifically for medical students interested in gastroenterology, but it can be used by those interested in other fields of medicine to better understand the significance of NSAIDs and aspirin. The author is very well versed in this area.” (Noah Settergren, Doody's Book Reviews, March, 2017)
Table of ContentsSection 1. Pharmacology and Mechanisms
Chapter 1. Chemistry, Pharmacodynamics, and Pharmacokinetics of NSAIDsSara Calatayud and Juan Vicente Esplugues
Chapter 2. Principles, Mechanisms of Action, and Future Prospects of Anti-Inflammatory DrugsBibiana Rius and Joan Clària
Section 2. Clinical Effects and Drug Safety
Chapter 3. Efficacy of NSAIDs in the Treatment of Rheumatic DiseasesMarc C. Hochberg and Lee S. Simon
Chapter 4. Adverse Effects of NSAIDs in the Gastrointestinal Tract: Risk Factors of Gastrointestinal Toxicity with NSAIDsSunny H. Wong and Francis K.L. Chan
Chapter 5. Adverse Effects of NSAIDs on the Cardiovascular SystemCarmelo Scarpignato and Corrado Blandizzi
Chapter 6. Safe Prescription of NSAIDs in Clinical PracticeMohammad Yaghoobi and Richard H. Hunt
Section 3. Aspirin
Chapter 7. NSAIDS and Aspirin: Recent Advances and Implications for Clinical ManagementKarsten Schrör and Michael Voelker
Chapter 8. Non-Prescription Analgesic Anti-inflammatory Drugs: Efficacy and SafetyDenis M. McCarthy
Chapter 9. Low-Dose Aspirin in the Cardiovascular SystemRuben Casado-Arroyo, Angel Lanas, and Pedro Brugada
Chapter 10. Adverse Effects of Low-Dose Aspirin in the Gastrointestinal TractKatsunori Iijima
Chapter 11. Aspirin in the Treatment and Prevention of Cardiovascular Disease: Need for Individual Clinical JudgmentsAngel Lanas and Charles H. Hennekens
Section 4. NSAIDS and Aspirin in Cancer Prevention
Chapter 12. Molecular and Experimental Basis for COX-Inhibition in CancerAnnalisa Bruno, Melania Dovizio, and Paola Patrignani
Chapter 13. Clinical Effects of NSAIDs and Coxibs in Colon Cancer PreventionElena Piazuelo and Angel Lanas
Chapter 14. Aspirin and the Prevention of Colorectal Cancer Paul J. Lochhead and Andrew T. Chan
Chapter 15. A Rational Approach for the Use of NSAIDs and/or Aspirin in Cancer Prevention in the Near Future: “Balancing Risk and Benefits”Elizabeth Half, Ahmad Fokra, and Nadir Arber
