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Book Synopsis
The very first examples of protein/DNA/inorganic nanocomposite materials are described. Surprisingly, the presence of DNA enhanced the properties of the bound protein. The layered inorganic solid, alpha-Zr(IV) phosphate (alpha-Zr(HPO4)2.H2O, abbreviated as alpha-ZrP) served as an excellent host for these studies, and the binding has been carried out under benign conditions (aqueous solutions at room temperature and neutral pH). These novel nanobiocomposite materials provide a simple method for the binding of DNA to negatively charged solids, and such approaches aid in engineering more effective synthetic materials for gene-delivery, RNA-delivery and drug delivery applications.

Novel Enzyme / DNA Inorganic Materials: A New

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    A Paperback / softback by Akhilesh Bhambhani, Chall V Kumar

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      View other formats and editions of Novel Enzyme / DNA Inorganic Materials: A New by Akhilesh Bhambhani

      Publisher: Nova Science Publishers Inc
      Publication Date: Publication Date: 01/05/2008
      ISBN13: 9781604561913, 978-1604561913
      ISBN10: 1604561912

      Description

      Book Synopsis
      The very first examples of protein/DNA/inorganic nanocomposite materials are described. Surprisingly, the presence of DNA enhanced the properties of the bound protein. The layered inorganic solid, alpha-Zr(IV) phosphate (alpha-Zr(HPO4)2.H2O, abbreviated as alpha-ZrP) served as an excellent host for these studies, and the binding has been carried out under benign conditions (aqueous solutions at room temperature and neutral pH). These novel nanobiocomposite materials provide a simple method for the binding of DNA to negatively charged solids, and such approaches aid in engineering more effective synthetic materials for gene-delivery, RNA-delivery and drug delivery applications.

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