Description
Book SynopsisApproximately half a million Americans suffer brain ischemic episodes every year. These brain strokes are the third leading cause of death in the United States and the number-one cause of permanent disability. Over the past decade, we have made extensive attempts to understand the biological mechanisms that underlie stroke-induced neuronal injury. This research has been benefited by the introduction of a variety of new technologies and assays aimed at deciphering the complex neuronal degenerating processes triggered by cerebral vascular disorders or other neurological diseases that produce ischemic episodes.
New Concepts in Cerebral Ischemia presents techniques and theories for understanding the various stages of early pathogenesis in order to design specific strategies to protect neurons from further injury. Short, specific, and comprehensive chapters provide detailed descriptions of the new methods employed in both basic and clinical research that are revolutionizing the fie
Table of ContentsGender Differences in Post-Ischemic and Post-Traumatic Brain Injury. Neonatal Hypoxic-Ischemic Insults and Its Mechanism. Neural Stem Cell Biology Provides Insights into New Therapeutic Strategies for Hypoxic-Ischemic Brain-Injury. Cellular and Molecular Mechanisms of Ischemic Tolerance. Excitotoxicity, Oxidative Stress, and Apoptosis in Ischemic Neuronal Death. Immediate and delayed Factors Causing Neuronal Death after Ischemic and Excitotoxic Insults. Mechanism of Zinc-Induced Neuronal Death. Cerebral Ischemia and Adenosine. Calpain and Caspase in Ischemic and Traumatic Brain Injury. The Potential Role of Hyperbaric Oxygen Therapy as an Adjunctive Treatment Modality for Stroke. Brain Inflammation, Cytokines, and p38AP Kinase Signaling in Stroke.