Description

Book Synopsis
This fully updated volume presents a wide range of methods for synthesis, surface modification, characterization and application of nano-sized materials (nanoparticles) in the life science and medical fields, with a focus on drug delivery and diagnostics.

Table of Contents

Part I: Synthesis of Nanoparticles and Their Applications in Biology and Medicine

1. Procedures for the Synthesis and Capping of Metal Nanoparticles

Claudia Gutiérrez-Wing, J. Jesús Velázquez-Salazar, and Miguel José-Yacamán

2. Antimicrobial Applications of Silver Nanoparticles to E. coli Colony Biofilms

James P. McEvoy, Kayra Genc, Priya Loi, and William J. Walker

3. Elastin-Based Antimicrobial Particles for Delivery of Bioactive Compounds

Raul Machado, André da Costa, Ana Margarida Pereira, José Carlos Rodriguez-Cabello, and Margarida Casal

4. Biomimetic Lipid Polymer Nanoparticles for Drug Delivery

Ana Maria Carmona-Ribeiro

5. Crotamine Cell-Penetrating Nanocarriers: Cancer-Targeting and Potential Biotechnological and/or Medical Applications

Mirian A.F. Hayashi, Joana D’Arc Campeiro, Lucas Carvalho Porta, Brian Szychowski, Wendel Andrade Alves, Eduardo B. Oliveira, Irina Kerkis, Marie-Christine Daniel, and Richard L. Karpel

6. Preparation of Lipid:Peptide:DNA (LPD) Nanoparticles and Their Use for Gene Transfection

Fan Zhang and Hao-Ying Li

7. Preparation of Hyaluronic Acid-Based Nanoparticles for Macrophage-Targeted MicroRNA Delivery and Transfection

Neha N. Parayath and Mansoor M. Amiji

8. Formulation and Characterization of Antithrombin Perfluorocarbon Nanoparticles

Alexander J. Wilson, Qingyu Zhou, Ian Vargas, Rohun Palekar, Ryan Grabau, Hua Pan, and Samuel A. Wickline

9. Biomedical In Vivo studies with ORMOSIL Nanoparticles Containing Active Agents

Sona Gandhi and Indrajit Roy

10. Preparation of Spray-Dried Nanoparticles for Efficient Drug Delivery to the Lungs

Hao-Ying Li and Fan Zhang

11. Synthesis and Evaluation of Airway-Targeted PLGA Nanoparticles for Drug Delivery in Obstructive Lung Diseases

Neeraj Vij

12. Synthesis and Evaluation of Dendrimers for Autophagy Augmentation and Alleviation of Obstructive Lung Diseases

Neeraj Vij

13. Synthesis of Poly (2-Hydroxyethyl Methacrylate) (PHEMA)-Based Superparamagnetic Nanoparticles for Biomedical and Pharmaceutical Applications

Rajesh Saini, Jaya Bajpai, and Anil K. Bajpai

Part II: Focus on the Nanoparticles Derivatization, Bio-Interface, and Nanotoxicity

14. The Molecular Dynamics Simulation of Peptides on Gold Nanosurfaces

Danilo Roccatano

15. Protein Immobilization on Gold Nanoparticles: Quantitative Analysis

Evan Decker, Chunsheng Bai, Lauren Nelless, Enrico Ferrari, and Mikhail Soloviev

16. Oriented Immobilization on Gold Nanoparticles of a Recombinant Therapeutic Zymogen

Elina Dosadina, Celetia Agyeiwaa, William Ferreira, Simon Cutting, Abdullah Jibawi, Enrico Ferrari, and Mikhail Soloviev

17. Directed and Modular Protein Immobilization on Gold and Silver Nanoparticles

Angela Saccardo, Wenwei Ma, Mikhail Soloviev, and Enrico Ferrari

18. In Vitro Labeling Mesenchymal Stem Cells with Superparamagnetic Iron Oxide Nanoparticles: Efficacy and Cytotoxicity

Jasmin

19. RNA Quantification Using Noble Metal Nanoprobes: Simultaneous Identification of Several Different mRNA Targets Using Color Multiplexing and Application to Chronic Myeloid Leukemia Diagnostics

Pedro Viana Baptista

20. Assessment of Toxicity of Nanoparticles Using Insects as Biological Models

Yan Zhou, Yan Chen, Aracely Rocha, Carlos J. Sanchez, and Hong Liang

Part III: Nanoparticles Characterization and Advanced Methods Development

21. Absolute Quantification of Gold Nanoparticles with Femtomolar Accuracy Using Inductively Coupled Plasma Atomic Emission Spectroscopy

Lee-Anne McCarthy, Andrew Dye, and Enrico Ferrari

22. NanoParticle Tracking Analysis for the Multiparameter Characterization and Counting of Nanoparticle Suspensions

Duncan Griffiths, Pauline Carnell-Morris, and Matthew Wright

23. Nanoparticle Bridges for Studying Electrical Properties of Organic Molecules and Gas Sensor Applications

Klaus Leifer, Syed Hassan Mujtaba Jafri, and Yuanyuan Han

24. Nanoparticle Characterization through Nano-Impact Electrochemistry: Tools and Methodology Development

Kevin A. Kirk, Tulashi Luitel, Farideh Hosseini Narouei, and Silvana Andreescu

25. Photostability of Semiconductor Quantum Dots in Response to UV Exposure

Julian Bailes

26. Gold Nanoclusters, Gold Nanoparticles, and Analytical Techniques for Their Characterization

Germán Plascencia-Villa, Rubén Mendoza-Cruz, Lourdes Bazán-Díaz, and Miguel José-Yacamán

27. Combining Nanoparticles with Colloidal Bubbles: A Short Review

Ekaterina Litau

28. Combination of Dark-Field and Confocal Microscopy for the Optical Detection of Silver and Titanium Nanoparticles in Mammalian Cells

Robert Martin Zucker and William K. Boyes

29. Detection of Silver and TiO2 Nanoparticles in Cells by Flow Cytometry

Robert Martin Zucker and William K. Boyes

Nanoparticles in Biology and Medicine

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      Description

      Book Synopsis
      This fully updated volume presents a wide range of methods for synthesis, surface modification, characterization and application of nano-sized materials (nanoparticles) in the life science and medical fields, with a focus on drug delivery and diagnostics.

      Table of Contents

      Part I: Synthesis of Nanoparticles and Their Applications in Biology and Medicine

      1. Procedures for the Synthesis and Capping of Metal Nanoparticles

      Claudia Gutiérrez-Wing, J. Jesús Velázquez-Salazar, and Miguel José-Yacamán

      2. Antimicrobial Applications of Silver Nanoparticles to E. coli Colony Biofilms

      James P. McEvoy, Kayra Genc, Priya Loi, and William J. Walker

      3. Elastin-Based Antimicrobial Particles for Delivery of Bioactive Compounds

      Raul Machado, André da Costa, Ana Margarida Pereira, José Carlos Rodriguez-Cabello, and Margarida Casal

      4. Biomimetic Lipid Polymer Nanoparticles for Drug Delivery

      Ana Maria Carmona-Ribeiro

      5. Crotamine Cell-Penetrating Nanocarriers: Cancer-Targeting and Potential Biotechnological and/or Medical Applications

      Mirian A.F. Hayashi, Joana D’Arc Campeiro, Lucas Carvalho Porta, Brian Szychowski, Wendel Andrade Alves, Eduardo B. Oliveira, Irina Kerkis, Marie-Christine Daniel, and Richard L. Karpel

      6. Preparation of Lipid:Peptide:DNA (LPD) Nanoparticles and Their Use for Gene Transfection

      Fan Zhang and Hao-Ying Li

      7. Preparation of Hyaluronic Acid-Based Nanoparticles for Macrophage-Targeted MicroRNA Delivery and Transfection

      Neha N. Parayath and Mansoor M. Amiji

      8. Formulation and Characterization of Antithrombin Perfluorocarbon Nanoparticles

      Alexander J. Wilson, Qingyu Zhou, Ian Vargas, Rohun Palekar, Ryan Grabau, Hua Pan, and Samuel A. Wickline

      9. Biomedical In Vivo studies with ORMOSIL Nanoparticles Containing Active Agents

      Sona Gandhi and Indrajit Roy

      10. Preparation of Spray-Dried Nanoparticles for Efficient Drug Delivery to the Lungs

      Hao-Ying Li and Fan Zhang

      11. Synthesis and Evaluation of Airway-Targeted PLGA Nanoparticles for Drug Delivery in Obstructive Lung Diseases

      Neeraj Vij

      12. Synthesis and Evaluation of Dendrimers for Autophagy Augmentation and Alleviation of Obstructive Lung Diseases

      Neeraj Vij

      13. Synthesis of Poly (2-Hydroxyethyl Methacrylate) (PHEMA)-Based Superparamagnetic Nanoparticles for Biomedical and Pharmaceutical Applications

      Rajesh Saini, Jaya Bajpai, and Anil K. Bajpai

      Part II: Focus on the Nanoparticles Derivatization, Bio-Interface, and Nanotoxicity

      14. The Molecular Dynamics Simulation of Peptides on Gold Nanosurfaces

      Danilo Roccatano

      15. Protein Immobilization on Gold Nanoparticles: Quantitative Analysis

      Evan Decker, Chunsheng Bai, Lauren Nelless, Enrico Ferrari, and Mikhail Soloviev

      16. Oriented Immobilization on Gold Nanoparticles of a Recombinant Therapeutic Zymogen

      Elina Dosadina, Celetia Agyeiwaa, William Ferreira, Simon Cutting, Abdullah Jibawi, Enrico Ferrari, and Mikhail Soloviev

      17. Directed and Modular Protein Immobilization on Gold and Silver Nanoparticles

      Angela Saccardo, Wenwei Ma, Mikhail Soloviev, and Enrico Ferrari

      18. In Vitro Labeling Mesenchymal Stem Cells with Superparamagnetic Iron Oxide Nanoparticles: Efficacy and Cytotoxicity

      Jasmin

      19. RNA Quantification Using Noble Metal Nanoprobes: Simultaneous Identification of Several Different mRNA Targets Using Color Multiplexing and Application to Chronic Myeloid Leukemia Diagnostics

      Pedro Viana Baptista

      20. Assessment of Toxicity of Nanoparticles Using Insects as Biological Models

      Yan Zhou, Yan Chen, Aracely Rocha, Carlos J. Sanchez, and Hong Liang

      Part III: Nanoparticles Characterization and Advanced Methods Development

      21. Absolute Quantification of Gold Nanoparticles with Femtomolar Accuracy Using Inductively Coupled Plasma Atomic Emission Spectroscopy

      Lee-Anne McCarthy, Andrew Dye, and Enrico Ferrari

      22. NanoParticle Tracking Analysis for the Multiparameter Characterization and Counting of Nanoparticle Suspensions

      Duncan Griffiths, Pauline Carnell-Morris, and Matthew Wright

      23. Nanoparticle Bridges for Studying Electrical Properties of Organic Molecules and Gas Sensor Applications

      Klaus Leifer, Syed Hassan Mujtaba Jafri, and Yuanyuan Han

      24. Nanoparticle Characterization through Nano-Impact Electrochemistry: Tools and Methodology Development

      Kevin A. Kirk, Tulashi Luitel, Farideh Hosseini Narouei, and Silvana Andreescu

      25. Photostability of Semiconductor Quantum Dots in Response to UV Exposure

      Julian Bailes

      26. Gold Nanoclusters, Gold Nanoparticles, and Analytical Techniques for Their Characterization

      Germán Plascencia-Villa, Rubén Mendoza-Cruz, Lourdes Bazán-Díaz, and Miguel José-Yacamán

      27. Combining Nanoparticles with Colloidal Bubbles: A Short Review

      Ekaterina Litau

      28. Combination of Dark-Field and Confocal Microscopy for the Optical Detection of Silver and Titanium Nanoparticles in Mammalian Cells

      Robert Martin Zucker and William K. Boyes

      29. Detection of Silver and TiO2 Nanoparticles in Cells by Flow Cytometry

      Robert Martin Zucker and William K. Boyes

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