Description
Book SynopsisPart 1. Basic Concepts of neurodegeneration and Alzheimer's disorder.- Basic anatomy and physiology of the central nervous system.- Neurodegenerative disorders: Types, Classification, and basic concepts.- Alzheimer's disorder: epidemiology, etiology, risk factors, future predictions.- Pathophysiology and underlying mechanisms: pathways to Alzheimer's plaque formation.- Correlation of Alzheimer's and other psychologic and non-psychologic conditions.- Part 2. Current scenario of Alzheimer's disorder.- Hurdles & strategies in treating Alzheimer's disorder.- Diagnosis of Alzheimer's, types of plaques and their detection, imaging techniques, and other tests.- Current drugs used: classification, pharmacology.- Approved drug regimens, combinations, and delivery systems for Alzheimer's disorder.- Traditional therapies for Alzheimer's disorder.- Part 3. Novel therapeutic approaches to Alzheimer's Therapy.- Nanotechnology in Alzheimer's.- Targeted drug delivery: amyloid beta targeting drugs, immunotherapy, anti-tau, and aggregation inhibitor, microtubule-stabilizing, and neuro-inflammation modulation.- Neuroprotective approach, microbiome therapy, and overcoming insulin resistance in the brain.- Nonpharmacological approaches: Brain stimulations, vagus nerve stimulation, magnetic and electrical transcranial stimulations.- Part 4. Alzheimer's drug development.- Understanding the potential targets of Alzheimer's disorder.- Upcoming nano and conventional drug delivery strategies for Alzheimer's disorder.- Animal models and ethics in the testing of drugs for Alzheimer's disorder.- Regulatory guidelines and approval process for drugs and formulations for AD.- Part 5. Future of Alzheimer's disorder.- Prevention and reduction of risk of AD: lifestyle changes, dietary changes, supplements, etc.- Natural medicines (phytoconstituents) and probiotics as the future of Alzheimer's Disorder.- Future barriers and possible solutions with recent advances in the field of Alzheimer's disease.
