Description
Book SynopsisMolecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of new targeted therapies, giving the reader a clear appreciation of how our understanding of the theory can be translated into new approaches for tackling the disease.The new edition draws on the latest research in cancer biology, highlighting fundamental concepts and re-emphasising pre-existing concepts. The book features a variety of learning features - ''Pause and think'', ''How do we know that?'', self-tests and activities - to help students engage with, and master, the concepts presented. The emphasis is on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. Molecular Biology of Cancer is supported by online resources and is available for students and institutions to purchase in a variety of formats. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks The online resources include:For students:- Multiple choice questions- Web links to additional cancer biology resourcesFor registered adopters of the book: Figures from the book, available to download
Trade ReviewI think this is a very well written book, the features are clear and concise and it's very easy and pleasing to follow and understand. It's covered a wide range of topics and the figures/diagrams are excellent. The features such as pause and think and pioneers in the field are such a great touch. * Blyth Richards, Student, Swansea University *
This textbook has extensive learning features that help to improve the reader's user experience and knowledge of scientific concepts. It is extremely well detailed and concise with a clear structure throughout. Specialised when needed, simplified whenever possible, highly recommend. * Daniel O'Neill, Student, Aberystwyth University *
This textbook is a clear and comprehensive overview of molecular biology in the context of cancer research and treatment. It is accessible to undergraduates and a helpful refresher for postgraduates as well. * Holly English, Student, University College Dublin *
I loved this book! It is stimulating and makes some very challenging work readable and accessible. The various learning features are useful and supportive, and serve to encourage a [strong] level of engagement. * Gary Edward Spencer, Student, Canterbury Christ Church University *
Overall I feel that the way in which the book explains complex mechanisms is outstanding. Where other textbooks can often leave you feeling perplexed, this textbook simplifies everything into manageable chunks. * Rebecca Kemp, Student, University of Nottingham *
This book provides a comprehensive grounding for students who want to investigate cancer mechanisms. It contains helpful active learning activities to ensure that students can understand, and most importantly, apply their knowledge to real life scenarios. * Dr Sarah Bailey, University of Surrey *
A good overview of the current understanding of the molecular events in cancer biology and how they are being exploited for targeting cancer treatments at the molecular level. * Dr Christopher Mee, University of Leicester *
Table of Contents1: Introduction 2: The cancer genome 3: Regulation of gene expression 4: Growth factor signaling and oncogenes 5: The cell cycle 6: Tumor suppressor genes 7: Apoptosis 8: Cancer stem cells and the regulation of self-renewal and differentiation pathways: focus on colon cancer and leukemias 9: Metastasis 10: Angiogenesis 11: Reprogrammed metabolism and diet 12: Tumor immunology and immunotherapy 13: Inflammation, infection, and the microbiome 14: Strategies and tools for research and drug development
