Description
Book SynopsisMicroarray technology provides researchers in the life sciences with a revolutionary tool for measuring gene expression. However, this highly developed process involves multiple steps, from sample selection to data analysis, each susceptible to potentially costly errors.
Trade Review"…a thought-provoking book…highly useful to statisticians, biologists, engineers, medical researchers, and medical scientists." (
Journal of Statistical Computation and Simulation, September 2005)
"The book may be recommended for all researchers and students working with the DNA microarray technology" (Annals of Biomedical Engineering, June 2005)
"...a useful source of ideas and potential issues." (Journal of the American Statistical Association, June 2005)
"This book is recommended [for] all libraries serving researchers using high-throughput techniques." (E-STREAMS, March 2005)
“…an essential laboratory resource for scientists studying gene regulation and for all experimental biologists interested in the emerging practical applications of microarrays.” (Engineering in Life Sciences, Vol.5, No.5, 2004)
"…offers practical guidance for each stage of planning and execution of microarray studies…" (Genetic Engineering News, Vol. 24, No. 6, March 15, 2004)
"…the breadth of issues encompassed by quality control in microarray studies are covered…a valuable systematic treatment of microarray quality control." (Drug Discovery and Development, March 2004)
Table of ContentsForeword ix
Preface xi
1 Quality of Biological Examples 1
2 Microarray Production: Quality of DNA and Printing 17
3 Quality of Microarray Hybridization 41
4 Scanners and data Acquisition 67
5 Image Analysis 79
6 Quality Control in data Analysis 97
Index 133
