DNA-Reco
Trade Review
"An impressive overview of the great diversity of current research." (Angewandte Chemie International Edition, February 2010)
"An essential part of the library for laboratories involved in bioinorganic and medicinal inorganic chemistry." (Chemistry World, September 2009)
Table of ContentsA Basic Structural and Kinetic Aspects 1. Sequence-Selective Binding of Transition Metal Complexes to DNA
2. Thermodynamic Models of Metal Ion -DNA.Interactions
3. Metal Ion Coordination in G-quadruplexes
4. Supramolecular Chemistry of Metal-Nucleobase Complexes
B Medical Applications
5. Platinum Drugs, Nucleotides, and DNA: the Role of Interligand Interactions,
nucleotides and DNA
6. Role of DNA Repair in Antitumor Effects of Platinum Drugs
7. Telomeres and Telomerase: Potential Targets for Platinum Complexes
8. Toward Photodynamic Therapy of Cancer with Platinum Group Metal Polyazine Complexes
9. Platinated Oligonucleotides: Synthesis and Applications for the Control of Gene
Expression
10. New Titanium and Ruthenium Anticancer Drugs and their Interaction with DNA
C DNA-Recognition - Nucleases and Sensors
11. Groove-Binding Ruthenium(II) Complexes as Probes of DNA Recognition
12. DNA Recognition and Binding by Peptide-Metal Complex conjugate
13. Artificial Restriction Agents - Hydrolytic Agents for DNA Cleavage
14. New Metallo-DNAzymes: Fundamental Studies of Metal-DNA Interactions and
Metal Sensing Applications
15. Two-metal Ion Dependent Catalysis in Nucleic Acid Enzymes
D Toxicological aspects
16. Mercury- DNA Interactions. Structural Studies on MercuryII -Mediated T-T Base-Pair with NMR Spectroscopy
17. Chromium-Induced DNA Damage and Repair
18. Arsenic and nickel: Mechanisms Affecting DNA Integrity
