Description
Book SynopsisThe facts about Lyme disease, from epidemiology to treatment to control Lyme borreliosis, popularly known as Lyme disease, remains the most commonly reported tick-transmitted infection in North America and Europe. A growing body of scientific and clinical evidence has facilitated early diagnosis and effective treatment. Nonetheless, there are a number of misconceptions about this infectious disease that have given rise to unproven, potentially dangerous alternative therapies. In Lyme Borreliosis in Europe and North America, a team of authors whose expertise spans basic research, epidemiology, and clinical practice has compiled evidence-based information on Lyme borreliosis.
Presents all the latest evidence needed to diagnose, treat, and prevent Lyme disease
Lyme Borreliosis in Europe and North America begins with a review of the disease''s epidemiology, the causative Borrelia genospecies, and tick vectors. It then explores pathogenesis, diag
Trade Review
“Finally, for those who consider themselves knowledgeable or who otherwise are interested in Lyme borreliosis, this book is an estimable presentation of what is known about Lyme borreliosis in Europe and North America.” (Clinical Infectious Diseases, 1 March 2013)
"This is an excellent addition to the field, written by experts and well researched and edited . . . The book makes a valuable contribution to the education of healthcare providers, from medical students to infectious disease experts. I highly recommend it." (Doody's, 30 September 2011)
Table of ContentsPreface vii
Acknowledgment ix
Contributors xi
1 THE EMERGENCE AND EPIDEMIOLOGY OF LYME BORRELIOSIS IN EUROPE AND NORTH AMERICA 1
Sunil K. Sood, Susan O'Connell, and Klaus Weber
2 THE SPIROCHETES AND VECTOR TICKS OF LYME BORRELIOSIS IN NATURE 37
Joseph Piesman and Pierre-Francois Humair
3 EARLY LYME BORRELIOSIS 53
Vijay K. Sikand and Robert R. Mu¨llegger
4 LYME CARDITIS 81
Fadi A. Haddad and Sunil K. Sood
5 NERVOUS SYSTEM LYME BORRELIOSIS 93
John J. Halperin and Leif Dotevall
6 LYME ARTHRITIS 115
Frank Dressler, Patricia I. Irigoyen, Norman T. Ilowite, and Hans-Iko Huppertz
7 BORRELIAL LYMPHOCYTOMA AND ACRODERMATITIS CHRONICA ATROPHICANS 135
Mark B. Salzman and Robert R. Mullegger
8 LYME BORRELIOSIS COINFECTIONS WITH ANAPLASMA AND BABESIA 149
Paul M. Lantos and Peter J. Krause
9 THE ROLE OF CULTURE AND NUCLEIC ACID AMPLIFICATION IN DIAGNOSIS OF LYME BORRELIOSIS 159
Gary P. Wormser and Guiqing Wang
10 SERODIAGNOSIS OF LYME BORRELIOSIS 185
Barbara J. B. Johnson, Maria E. Aguero-Rosenfeld, and Bettina Wilske
11 PROGNOSIS OF PERSONS WITH LYME BORRELIOSIS 213
Eugene D. Shapiro and Sunil K. Sood
12 PREVENTION OF LYME BORRELIOSIS 225
Sunil K. Sood
Index 245