Description

Book Synopsis
Behind the neologism ribozymes lies a family of fascinating molecules, ribo-enzymes, which have been relatively little studied. These catalytically active RNAs are found in all strata of life, from viruses to the human genome.

At the end of the 1970s, the discovery of a catalytic RNA nestled in an intron, followed by another involved in the maturation of transfer RNAs, led to the discovery of new ribozymes and the transition from a strictly proteocentric vision, inherited from the dogma of molecular biology, to a more nucleocentric one. Since then, a variety of ribozymes have been identified in genomes, where their functions often remain mysterious.

Looking at Ribozymes traces the discovery of these molecules and presents a picture of their functional diversity, catalytic mechanisms and distribution within the tree of life.

Looking at Ribozymes

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    A Hardback by Benoît Masquida

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      Book details

      Publisher ISTE Ltd.
      Published 3 November 2024
      ISBN-13 9781786309778
      978-1786309778
      ISBN-10 1786309777
      Also in:
      Chemistry

      Description

      Book Synopsis
      Behind the neologism ribozymes lies a family of fascinating molecules, ribo-enzymes, which have been relatively little studied. These catalytically active RNAs are found in all strata of life, from viruses to the human genome.

      At the end of the 1970s, the discovery of a catalytic RNA nestled in an intron, followed by another involved in the maturation of transfer RNAs, led to the discovery of new ribozymes and the transition from a strictly proteocentric vision, inherited from the dogma of molecular biology, to a more nucleocentric one. Since then, a variety of ribozymes have been identified in genomes, where their functions often remain mysterious.

      Looking at Ribozymes traces the discovery of these molecules and presents a picture of their functional diversity, catalytic mechanisms and distribution within the tree of life.

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