Description

Book Synopsis

Properties and Application of Pseudotyped Lentiviral Vectors.- Production and Purification of Lentiviral Vectors.- Lentiviral Vector Administration into the Mouse Brain.- Stereotaxic Injection of Lentiviral Vectors into the Primate Brain.- Optimized Lentiviral Vector Production Using Dual-Pseudotyping with VSV-G and Sendai Virus HN Glycoproteins for Enhanced Gene Delivery in Diverse Cell Types.- Preparation of Lentiviral Vectors for the Generation of Transgenic Cynomolgus Monkeys.- Ubiquitous and Brain Cell-Type-Specific Promoters and Enhancers in Lentiviral Vectors.- Efficient Labeling of Somatodendritic Membranes of the Central Neurons.- Visualization of Selective Neural Pathways by Double Viral Infection Method.- Lentivirus-Mediated Measurement of Transcription Factor Activity in the Brain.- Birth Date-Dependent Tracing of Neuronal Cell Lineage.- Application of Lentivirus Vectors to Adult Neurogenesis and Manipulation of Neural Stem Cells.- Direct Reprogramming of Microglia into Neurons.- Selective Neural Pathway Targeting by Using Lentiviral Vectors.- Synaptic Silencing with Transactivation of Tetanus Neurotoxin for Pathway-Selective Manipulation.- Optogenetic Approach for In Vivo Manipulation of Neural Circuits Using Lentiviral Vectors.- Selective Chemogenetic Blockade of Cerebello-Rubral Pathway by Double-Virus Infection Method Using Lentivirus and Adeno-Associated Virus in Rats.- Development of a Gene Therapy with Lentiviral Vectors for Spinocerebellar Ataxias.- Lentiviral Vector-Mediated Gene Delivery for iPSC-Related Neuroscience Research.- Phase 1/2a Clinical Trial Protocol for Lentiviral Vector-Based Retinal Gene Therapy to Slow the Progression of Retinitis Pigmentosa.- CAR-T Cell Therapy for Central Nervous System Tumors.

Lentiviral Vectors

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    A Hardback by Kazuto Kobayashi

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      Book details

      Publisher Humana
      Published 21 October 2025
      ISBN-13 9781071648063
      978-1071648063
      Also in:
      Neurosciences

      Description

      Book Synopsis

      Properties and Application of Pseudotyped Lentiviral Vectors.- Production and Purification of Lentiviral Vectors.- Lentiviral Vector Administration into the Mouse Brain.- Stereotaxic Injection of Lentiviral Vectors into the Primate Brain.- Optimized Lentiviral Vector Production Using Dual-Pseudotyping with VSV-G and Sendai Virus HN Glycoproteins for Enhanced Gene Delivery in Diverse Cell Types.- Preparation of Lentiviral Vectors for the Generation of Transgenic Cynomolgus Monkeys.- Ubiquitous and Brain Cell-Type-Specific Promoters and Enhancers in Lentiviral Vectors.- Efficient Labeling of Somatodendritic Membranes of the Central Neurons.- Visualization of Selective Neural Pathways by Double Viral Infection Method.- Lentivirus-Mediated Measurement of Transcription Factor Activity in the Brain.- Birth Date-Dependent Tracing of Neuronal Cell Lineage.- Application of Lentivirus Vectors to Adult Neurogenesis and Manipulation of Neural Stem Cells.- Direct Reprogramming of Microglia into Neurons.- Selective Neural Pathway Targeting by Using Lentiviral Vectors.- Synaptic Silencing with Transactivation of Tetanus Neurotoxin for Pathway-Selective Manipulation.- Optogenetic Approach for In Vivo Manipulation of Neural Circuits Using Lentiviral Vectors.- Selective Chemogenetic Blockade of Cerebello-Rubral Pathway by Double-Virus Infection Method Using Lentivirus and Adeno-Associated Virus in Rats.- Development of a Gene Therapy with Lentiviral Vectors for Spinocerebellar Ataxias.- Lentiviral Vector-Mediated Gene Delivery for iPSC-Related Neuroscience Research.- Phase 1/2a Clinical Trial Protocol for Lentiviral Vector-Based Retinal Gene Therapy to Slow the Progression of Retinitis Pigmentosa.- CAR-T Cell Therapy for Central Nervous System Tumors.

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