Description

Book Synopsis
Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. Laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. In this book, the authors present current research in the study of the structure, biological activity and role in disease of laminins. Topics include the key roles of laminins from embryos to adult skeletal muscle; Laminin-332 and integrins; anosmin-1 and galectin-1 as laminin interactors in nervous system development and pathology; loss of laminin alpha two; role of laminin in epithelial morphogenesis in the liver; laminins in uterine remodelling and embryo development during pregnancy; human gingival laminin-332 degradation by oral bacteria; and laminins as a modulator of the axonal response to guidance cues.

Laminins: Structure, Biological Activity &Role in

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    A Hardback by Demetrius C Adams, Emil O Garcia

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      View other formats and editions of Laminins: Structure, Biological Activity &Role in by Demetrius C Adams

      Publisher: Nova Science Publishers Inc
      Publication Date: Publication Date: 19/06/2013
      ISBN13: 9781626185685, 978-1626185685
      ISBN10: 1626185689

      Description

      Book Synopsis
      Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. Laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. In this book, the authors present current research in the study of the structure, biological activity and role in disease of laminins. Topics include the key roles of laminins from embryos to adult skeletal muscle; Laminin-332 and integrins; anosmin-1 and galectin-1 as laminin interactors in nervous system development and pathology; loss of laminin alpha two; role of laminin in epithelial morphogenesis in the liver; laminins in uterine remodelling and embryo development during pregnancy; human gingival laminin-332 degradation by oral bacteria; and laminins as a modulator of the axonal response to guidance cues.

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