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Book Synopsis
The human skin is constantly exposed to a large number of external pathogens, due to daily contact with the environment. The observation that extensive skin infections are relatively rare suggests the presence of an efficient host defence system at the skin surface. Recent findings indicate the importance of keratinocytes as effectors of innate immunity, but also as regulators of acquired immune responses, inflammation and wound repair. This book considers the current findings regarding the role of keratinocytes in the epidermis with special interest to mechanisms involved in host defence. Finally, the clinical relevance of the functions of keratinocytes in the innate immunity is also discussed.

Keratinocytes: Structure, Molecular Mechanisms &

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A Hardback by Elia Ranzato

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    View other formats and editions of Keratinocytes: Structure, Molecular Mechanisms & by Elia Ranzato

    Publisher: Nova Science Publishers Inc
    Publication Date: 01/07/2013
    ISBN13: 9781626187986, 978-1626187986
    ISBN10: 1626187983
    Also in:
    Cellular biology (cytology)

    Description

    Book Synopsis
    The human skin is constantly exposed to a large number of external pathogens, due to daily contact with the environment. The observation that extensive skin infections are relatively rare suggests the presence of an efficient host defence system at the skin surface. Recent findings indicate the importance of keratinocytes as effectors of innate immunity, but also as regulators of acquired immune responses, inflammation and wound repair. This book considers the current findings regarding the role of keratinocytes in the epidermis with special interest to mechanisms involved in host defence. Finally, the clinical relevance of the functions of keratinocytes in the innate immunity is also discussed.

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