Description
Book SynopsisIon-Pair Chromatography (IPC) is a rapidly evolving method for difficult analyses of organic and inorganic ions and ionogenic, neutral, and zwitterionic compounds. The possibilities for this technology continue to grow as novel ion-pair reagents and strategies are introduced at an accelerated level. Compensating for a dearth in the literature, Ion-Pair Chromatography and Related Techniques details the basics and the evolution of this established and easily tunable technique and explains its influence on similar methods.
Theoretical modeling to application
Providing a thorough exploration of the multiplicity of interactions involved in an IPC system, this book emphasizes the progress from theoretical modeling to application. It explores the practical potential of IPC in the life science, medicine, pharmacology, forensic, food, and environmental sectors. It examines the upgrade of column technology and instrumentation to im
Trade Review
"… provides a broad coverage of the subject of IPC with regard to theoretical features, the parameters influencing the results and the applications. The reader will find a discussion of all aspects of IPC, beginning with the theoretical basis of this technique and its retention mechanism. The author introduces to the reader all the issues connected with stationary phases, ionpair reagents, organic modifiers, the pH of the eluent, temperature, and various detection techniques which may be used in IPC. One can also find much practical advice on how to start with IPC and how to improve results by the use of IPC."
—Analytical and Bioanalytical Chemistry, April 2012
Table of ContentsIntroduction. Electrolyte Solutions and Historical Concept of Ion-Pairing. Retention Modeling as Function of Mobile Phase Composition. Modeling of Retention as a Function of Analyte Nature. Stationary Phases. Developments in Column Technology and Fast IPC. Ion Pairing Reagents. Organic Modifiers. Role of Eluent pH in IPC. Temperature. Special IPC Modes and Variations. Detection and Combination. Examples of Applications. IPC versus Competitive Techniques. Ion-Pairing in Different Analytical Techniques. Non-Separative Applications of IPC. Conclusions and Future Research Needs.
