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Book Synopsis
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in acute inflammation. It is secreted by T cells and macrophages during infection and after trauma. It is responsible for activation of B cells and other immune cells. In this book, the authors discuss the genetics, clinical applications and role in disease of interleukin-6. Topics include IL-6 inhibitors as novel generation of treatment strategies; the role of interleukin-6 in postoperative delirium; elevated interleukin-6 levels as a consequence of obesity and insulin resistance; the effects of IL-6 on respiratory mechanics in rats; and IL-6 targeting strategy for rheumatoid arthritis and various immune-mediated diseases.

Interleukin-6: Genetics, Clinical Applications &

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    A Hardback by Jovanni D'Aquino, Edward N DeVito

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      Publisher: Nova Science Publishers Inc
      Publication Date: 15/05/2013
      ISBN13: 9781624175923, 978-1624175923
      ISBN10: 1624175929
      Also in:
      Science & Nature Biochemistry

      Description

      Book Synopsis
      Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in acute inflammation. It is secreted by T cells and macrophages during infection and after trauma. It is responsible for activation of B cells and other immune cells. In this book, the authors discuss the genetics, clinical applications and role in disease of interleukin-6. Topics include IL-6 inhibitors as novel generation of treatment strategies; the role of interleukin-6 in postoperative delirium; elevated interleukin-6 levels as a consequence of obesity and insulin resistance; the effects of IL-6 on respiratory mechanics in rats; and IL-6 targeting strategy for rheumatoid arthritis and various immune-mediated diseases.

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