Description
Book SynopsisOffers information on the developments, innovations, and clinical procedures in image-guided and adaptive radiation therapy. This book discusses the use of implanted fiducial markers, management of respiratory motion, image-guided stereotactic radiosurgery and stereotactic body radiation therapy.
Trade Review"The capacity to use image data during the delivery of radiation therapy represents a major development in radiation oncology, and along with adaptive radiotherapy, it is the topic of this review on
Image Guided Adaptive Radiation Therapy (IGART). The book is edited by Robert Timmerman and Lei Xing, with 22 chapters by 71 authors grouped into three parts. Part I is an overview of image-guided adaptive radiotherapy (IGART), with two informative introductory chapters summarizing its rationale, methods, current status, and future expectations. It explains current image-guided radiotherapy (IGRT) and IGART methods, with the assistance of a table that allows comparisons among different methods. Next are several chapters, each explaining a major topic in IGART, such as errors and margins, management of respiratory motion, IGART in brachytherapy, stereotactic radiosurgery, and stereotactic body RT, and implanted fiducial markers. The justification for IGART is to ‘‘reduce the uncertainty and treatment margins,’’ by addressing three issues—tumor delineation, interfractional, and intrafractional uncertainties, and the chapter on errors and margins is particularly well-written, identifying the gain that is achieved and potentially achievable by addressing each of these three issues.
The second part of the book is organized by anatomic site, with chapters focusing on IGART for head-and-neck, lung, breast, liver, gastrointestinal, genitourinary, gynecologic, central nervous system, and pediatric cancers. The type and amount of uncertainties, treatment margins, possible IGART applications, and potential clinical gain from IGART are explored for each treatment site...overall, they convey a thorough description of the role of IGART in each of these anatomic sites.
Part III discusses the technical and practical challenges encountered when introducing IGART to the clinic. IGART applications, especially the frequent plan adaptations, require effective solutions to manage challenges such as increased workload, reimbursement for the additional work, increased complexity of operation and equipment, an increased possibility of error, and more difficult data management and access. A long chapter outlines seven commercially available IGART platforms, each in a separate subsection written by the developers of these technologies...learning the systems’ existing capabilities, as well as the vendors’ works in progress, is informative."
"The book provides high-quality information and perspective, with coverage both wide and deep on topics of interest. Both the novice and experienced users of IGART can learn from this book, and the book should be a source of ideas for investigators."
Ergun Ahunbay, Ph.D.
Department of Radiation Oncology
Medical College of Wisconsin
Milwaukee, WI
The capacity to use image data during the delivery of radiation therapy represents a major development in radiation oncology, and along with adaptive radiotherapy, it is the topic of this review on
Image Guided Adaptive Radiation Therapy (IGART). The book is edited by Robert Timmerman and Lei Xing, with 22 chapters by 71 authors grouped into three parts. Part I is an overview of image-guided adaptive radiotherapy (IGART), with two informative introductory chapters summarizing its rationale, methods, current status, and future expectations. It explains current image-guided radiotherapy (IGRT) and IGART methods, with the assistance of a table that allows comparisons among different methods. Next are several chapters, each explaining a major topic in IGART, such as errors and margins, management of respiratory motion, IGART in brachytherapy, stereotactic radiosurgery, and stereotactic body RT, and implanted fiducial markers. The justification for IGART is to ‘‘reduce the uncertainty and treatment margins,’’ by addressing three issues—tumor delineation, interfractional, and intrafractional uncertainties, and the chapter on errors and margins is particularly well-written, identifying the gain that is achieved and potentially achievable by addressing each of these three issues.
The second part of the book is organized by anatomic site, with chapters focusing on IGART for head-and-neck, lung, breast, liver, gastrointestinal, genitourinary, gynecologic, central nervous system, and pediatric cancers. The type and amount of uncertainties, treatment margins, possible IGART applications, and potential clinical gain from IGART are explored for each treatment site...overall, they convey a thorough description of the role of IGART in each of these anatomic sites.
Part III discusses the technical and practical challenges encountered when introducing IGART to the clinic. IGART applications, especially the frequent plan adaptations, require effective solutions to manage challenges such as increased workload, reimbursement for the additional work, increased complexity of operation and equipment, an increased possibility of error, and more difficult data management and access. A long chapter outlines seven commercially available IGART platforms, each in a separate subsection written by the developers of these technologies...learning the systems’ existing capabilities, as well as the vendors’ works in progress, is informative.
...The book provides high-quality information and perspective, with coverage both wide and deep on topics of interest. Both the novice and experienced users of IGART can learn from this book, and the book should be a source of ideas for investigators.
Ergun Ahunbay, Ph.D.
Department of Radiation Oncology
Medical College of Wisconsin
Milwaukee, WI -- Ergun Ahunbay, Ph.D. * Int. J. Radiation Oncology Biol. Phys., Vol. 80, No. 4, p. 1278 *
Table of ContentsPart I: METHODOLOGY AND TECHNOLOGY FOR IMAGE-GUIDED ADAPTIVE RADIATION THERAPY
Chapter 1: Introduction to Image-Guided and Adaptive Radiotherapy
Martin J. Murphy and Tianfang Li
Chapter 2: Image-Guided Adaptive Radiation Therapy and Practical Perspectives
Lei Xing, Louis Lee, and Robert Timmerman
Chapter 3: Errors, Margins, Localization and Correction
Jan-Jakob Sonke and Marcel van Herk
Chapter 4: Use of Implanted Fiducial Markers in IGRT
Daniel Low and James Balter
Chapter 5: Management of Respiratory Motion in Radiation Therapy
Gig S. Mageras and Paul J. Keall
Chapter 6: Image-Guided Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy
T.D. Solberg, B. Kavanagh, and P.M. Medin
Chapter 7: Three-Dimensional Conformal Brachytherapy: Current Trends and Future Promise
Jeffrey F. Williamson and Robert Cormack
Chapter 8: Target Definition and Localization
Daniel R. Gomez, K.S. Clifford Chao, and Nancy Y. Lee
Chapter 9: PET/CT and Biologically Conformal Radiation Therapy
Marco Trovo, Jeffrey Bradley, and Mitchell Machtay
Part II. IMAGE-GUIDED ADAPTIVE RADIATION THERAPY IN CLINICAL PRACTICE
Chapter 10: Head and Neck Cancers
Ping Xia and Quynh-Thu Le
Chapter 11: Lung Cancers
Steve Jiang, Loren Mell, and Ajay Sandhu
Chapter 12: Breast Cancers
Sua Yoo, Jinli Ma, Lawrence Marks, and Fang-Fang Yin
Chapter 13: Liver Malignancies
Kristy K. Brock and Laura A. Dawson
Chapter 14: Non-Hepatic Gastrointestinal Malignancies
Daniel T. Chang, Devin S. Schellenberg, and Albert C. Koong
Chapter 15: Genitourinary Cancers
Lei Dong and Jeff M. Michalski
Chapter 16: Gynecologic Malignancies
Loren K. Mell, Josh Haslam, John Roeske, and Arno J. Mundt
Chapter 17: Central Nervous System Tumors
Yoshiya Yamada, D. Michael Lovelock, Jenghwa Chang, and Mark H. Bilsky
Chapter 18: Pediatric Cancers
Thomas Merchant and Chris Beltran
Part III. ESTABLISHING AN IMAGE-GUIDED ADAPTIVE RADIATION THERAPY PROGRAM
Chapter 19: Platforms for Image-Guided and Adaptive Radiation Therapy
Warren Kilby, Calvin R. Maurer, C. Amies, A. Bani-Hashemi, B. Groh, T. Tuecking, K.J. Ruchala, W. Lu, G.H. Olivera, T.R. Mackie, and Peter Munro
Chapter 20: Quality Assurance of Image-Guided Adaptive Radiation
Douglas J. Moseley, Jean-Pierre Bissonnette, Michael B. Sharpe, and David A. Jaffray
Chapter 21: Information Systems and Data Management
Sam Brain and Bruce H. Curran
Chapter 22: Image-Guided and Adaptive Radiation Therapy Billing and Reimbursement
Chet Szerlag, Luis Canovas, and Claire Mendenhall
