Description
Book SynopsisPart I. History of HAI.- Philosophy and rationale for liver-directed therapy (includes history of catheter-based chemotherapy delivery).- Transarterial therapies and Early History/Trials of HAI.- Device Development: development of implantable reservoir-based pump.- Optimization of therapy: Drug development, pharmacokinetics, pharmacodynamics.- Part II. HAI Perioperative and Operative Considerations.- Preoperative Evaluation.- Conduct of Open HAIP placement.- Conduct of MIS HAIP placement.- Concurrent procedures and perioperative care/postoperative considerations.- Pre-HAI Perfusion Scans.- HAI Pump-Specific Complications and Management.- Part III. HAI Delivery.- HAI Drugs.- Concurrent Systemic Therapy.- Duration, maintenance, and secondary use of HAI.- Part IV. HAI Patient Selection and Efficacy.- Unresectable CRLM.- Adjuvant HAI for resected CRLM.- Intrahepatic cholangiocarcinoma.- Other indications: HCC, NET, Breast, Pancreas Cancer.- Part V. Long-Term Consequences of HAI.- Biliary sclerosis.- Hepatic Failure.- Termination of HAI and Pump Removal.- Transplant after HAI.- Part VI. Starting a New HAI Program.- Recruitment of a team.- Device and drug procurement.- Regulatory/IRB Considerations.- Training a new HAI team.- HAI Site Visits.- Early Patient Selection.- Patient education.- International Perspective.- Part VII. The Future of HAI.- Device development: the future.- Drug development.- Part VIII. Alternative Approaches to HAI delivery.- Complete percutaneous delivery.- Reservoir-less ports.- Part IX. HAI Video Atlas.- Open HAI pump implantation.- Robotic HAI pump implantation.- Accessing HAI pump reservoir.- Accessing HAI pump bolus port.- Priming the HAI pump.
