Description
Book SynopsisHelicobacter pylori is a globally significant pathogen that infects half of the population of the world. Its recognition enabled the development of new therapeutic and preventative strategies for serious health conditions such as gastric cancer, of which it is the major causative agent. Providing a broad overview of the current understanding of this pathogen and emphasising its world health impacts, this book explores a range of topics including virulence factors, vaccine development and obstacles, epidemiology, antibiotic resistance and the role of Nod receptors, with a foreword by Barry Marshall, the Nobel Laureate and co-discoverer of H. pylori. It is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.
Table of ContentsI: PATHOLOGIES AND TREATMENT 1: Epidemiology of Helicobacter pylori infection - Hoda Malaty 2: Helicobacter pylori infection in Asia - Kwong Fock 3: Gastric adenocarcinoma - Pelayo Correa and M. Blanca Piazuelo 4: Antimicrobial resistance and approaches to treatment - Francis Megraud 5: Extragastric manifestations of Helicobacter pylori infection - Hazel Mitchell, Nadeem Kaakoush and Philip Sutton II: HOST RESPONSE 6: Helicobacter pylori-induced acquired immunity and immunoregulation - Karen Robinson and John C Atherton 7: Host genetic factors and susceptibility to Helicobacter pylori pathogenesis - Philip Sutton, Alison L Every and Stacey N Harbour 8: Innate immune initiators and effectors in H. pylori infection - Maria Kaparakis, Cody C. Allison, Melanie L. Hutton and Richard L. Ferrero 9: Helicobacter pylori vaccines - Thomas Blanchard and John G Nedrud III: BACTERIAL DEFENCE 10: Lipopolysaccharides of Helicobacter pylori: importance in gastric adaptation and pathogenesis - Anthony P Moran 11: Virulence factors of Helicobacter pylori - Steffen Backert, Hitomi Mimuro, Dawn A Israel and Richard M Peek, Jr. 12: Helicobacter pylori adhesion to the gastric surface - Sara K Lindén, Anna Arnqvist, Susanne Teneberg and Anthony P. Moran 13: Helicobacteromics - Hilde de Reuse, Markus M Heimesaat and Stefan Bereswill
