Five new chapters provide detailed coverage of liver disease, diabetes education, bariatric surgery, diabetes and cancer, and the use of incretin-based therapies and SGLT2 Inhibitors in the manag
Table of Contents
Preface ix
Key to the boxes x
List of abbreviations xi
Part 1: Introduction to diabetes 1
1 Introduction to diabetes 3
2 History of diabetes 6
3 Diagnosis and classification of diabetes 10
4 Public health aspects of diabetes 17
5 Normal physiology of insulin secretion and action, and the incretin effect 23
6 Epidemiology and aetiology of type 1 diabetes 35
7 Epidemiology and aetiology of type 2 diabetes 46
8 Other types of diabetes 57
Part 2: Metabolic control and complications 65
9 Diabetes control and its measurement 67
10 Management of type 1 diabetes 78
11 Management of type 2 diabetes 90
12 Diabetic ketoacidosis (DKA), hyperglycaemic hyperosmolar state (HHS)and lactic acidosis 100
13 Hypoglycaemia 110
14 Causes of complications 118
15 Diabetic eye disease 129
16 Diabetic nephropathy 141
17 Diabetic neuropathy 155
18 Blood lipid abnormalities 162
19 Hypertension in diabetes 168
20 Macrovascular disease in diabetes 179
21 Foot problems in diabetes 189
22 Sexual problems in diabetes 196
23 Gastrointestinal problems in diabetes 204
24 Non-alcoholic liver disease (NAFLD) 211
25 Diabetes and cancer 217
26 Skin and connective tissue disorders in diabetes 221
27 Psychological and psychiatric problems in diabetes 227
Part 3: The spectrum and organisation of diabetes care 235
28 Intercurrent situations that affect diabetes control 237
29 Pregnancy and diabetes 247
30 Diabetes in childhood and adolescence 257
31 Diabetes in old age 265
32 Diabetes and lifestyle 269
33 Organisation of diabetes care: integrating diabetes service 275
34 Transplantation and stem cell therapy 282
Index 288
