Description

Book Synopsis

Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web.

Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature.

New tables for this edition:

  • Chrom

    Table of Contents

    SECTION I: AMINO ACIDS, PEPTIDES, AND PROTEINS

    Properties of Amino Acids

    Data on the Naturally Occurring Amino Acids

    Coefficients of Solubility Equations of Certain Amino Acids in Water

    Heat Capacities, Absolute Entropies, and Entropies of Formation of Amino Acids and Related Compounds

    Heat of Combustion, Enthalpy, and Free Energy of Formation of Amino Acids and Related Compounds

    Solubilities of Amino Acids in Water at Various Temperatures

    Heats of Solution of Amino Acids in Aqueous Solution at 25°C

    Free Energies of Solution and Standard Free Energy of Formation of Amino Acids in Aqueous Solution at 25°C

    Far Ultraviolet Absorption Spectra of Amino Acids

    UV Absorption Characteristics of N-Acetyl Methyl Esters of the Aromatic Amino Acids, Cystine, and of N-Acetylcysteine

    Numerical Values of the Absorbances of the Aromatic Amino Acids in Acid, Neutral, and Alkaline Solutions

    Hydrophobicities of Amino Acids and Proteins

    Partial Volumes of Amino Acids

    Deamidation of Asparagine

    Michael Reactions of Proteins

    Molecular Weights of Proteins and Some Other Materials Including Sedimentation, Diffusion, and Frictional Coefficients and Partial Specific Volumes

    Molar Absorptivity and A1cm 1% Values for Proteins at Selected Wavelengths of the Ultraviolet and Visible Region

    Temperature Coefficients of Apparent Partial Specific Volumes of Proteins Expressed in ml/g/deg (dV/dT)

    Protein pK Values

    Intrinsic Viscosity of Proteins

    Infrared Spectra of Proteins

    Volume Changes for Some Macromolecule Association Reactions

    Assay of Solution Protein Concentration

    Spectrophotometric Determination of Protein Concentration in the Short-Wavelength Ultraviolet

    SECTION II: ENZYMES

    Turnover of Enzymes in Tissues

    Molecular Turnover of Cytochromes in Animals

    Matrix Metalloproteinases

    Proteases in the Interstitial Space

    Enzymes in Synthetic OrganicChemistry

    Therapeutic Enzymes

    Protease Inhibitors and Protease Inhibitor Cocktails

    SECTION III: LIPIDOMICS AND LIPIDOMES

    Evolution of the Classification and Nomenclature of Lipids

    A Brief Glossary for Lipidomics

    A Comprehensive Classification System for Lipids

    Properties of Fatty Acids and Their Methyl Esters

    Densities, Specific Volumes, and Temperature Coefficients of Fatty Acids from C8 to C12

    Composition and Properties of Common Oils and Fats

    Spectral Properties of Fatty Acids

    IR Active Bands of Phosphatidylethanolamines (PE)

    Concentration of Some Fatty Acids in Human Blood, Blood Plasma or Blood Serum

    Some Unusual Fatty Acid Structures

    SECTION IV: VITAMINS AND COE NZYMES

    Properties of Vitamins

    Biological Characteristics of Vitamins

    Vitamers

    Vitamin Names Discarded

    SECTION V: NUCLEIC ACIDS

    Some Definitions for Nucleic Acids

    UV Spectral Characteristics and Acidic Dissociation Constants of 280 Alkyl Bases, Nucleosides, and Nucleotides

    Ultraviolet Absorbance of Oligonucleotides Containing 2′-O-Methylpentose Residues

    Spectrophotometric Constants of Ribonucleotides

    Purines, Pyrimidines, Nucleosides, and Nucleotides: Physical Constants and Spectral Properties

    Chemical Modification of Nucleic Acids

    Polymerase Chain Reaction

    Gene Editing

    SECTION VI: GLYCOSCIENCE

    Nomenclature of Carbohydrates

    Chemical Modification of Carbohydrates

    Some Properties of Glycosaminoglycans

    Sugar Mimetics

    Intrinsic Viscosity of Polysaccharides

    SECTION VII: CHEMICAL BIOLOGY AND DRUG DESIGN

    Unnatural Amino Acids for Incorporation into Proteins

    Structures and Symbols for Synthetic Amino Acids Incorporated into Synthetic Polypeptides

    Properties of the α-Keto Acid Analogs of Amino Acids

    α,β-Unsaturated Amino Acids

    Amino Acid Antagonists

    Particle Diameter

    Weights of Cells and Cell Constituents

    Click Chemistry

    A Listing of Log P Values, Water Solubility, and Molecular Weight for Some Selected Chemicals

    SECTION VIII: PHYSICAL AND CHEMICAL DATA

    IUBMB-IUPAC Joint Commission on Biochemical Nomenclature (JCBN) Recommendations for Nomenclature and Tables in Biochemical Thermodynamics

    Standard Transformed Gibbs Energies of Formation for Biochemical Reactants

    Enthalpy, Entropy, and Free Energy Values for Biochemical Redox Reactions

    Oxidation-Reduction Potentials, Absorbance Bands, and Molar Absorbance of Compounds Used in Biochemical Studies

    Calorimetric ΔH Values Accompanying Conformational Changes of Macromolecules in Solution

    Free Energies of Hydrolysis and Decarboxylation

    Deci-Normal Solutions of Oxidation and Reduction Reagents

    Guidelines for Potentiometric Measurements in Suspensions Part A — The Suspension Effect

    Ionization Constants of Acids and Bases

    Guidelines for NMR Measurements for Determination of High and Low pKa Values

    Measurement and Interpretation of Electrokinetic Phenomena

    Measurement of pH Definition, Standards, and Procedures

    General Comments on Buffers

    List of Buffers

    Bronsted Acidities

    Buffer Solutions

    Amine Buffers Useful for Biological Research

    Preparation of Buffers for Use in Enzyme Studies

    Indicators for Volumetric Work and pH Determinations

    Acid and Base Indicators

    Specific Gravity of Liquids

    Properties of Some Solvents

    Chemicals Commonly Used in Biochemistry and Molecular Biology and their Properties

    Common Detergents Used in Biochemical Research

    Some Properties of Detergents and Surfactants Used in Biochemistry and Molecular Biology

    Some Biological Stains and Dyes

    Mordant Dyes

    Metal Chelating Agents

    Metallomics: Guidelines for Terminology and Critical Evaluation of Analytical Chemistry Approaches (IUPAC Technical Report)

    Water

    General Information on Spectroscopy

    Plastics

    Chemical and Physical Properties of Various Commercial Plastics

    Chemical Resistance of Plastics

    Generic Source-Based Nomenclature for Polymers

    Definitions of Terms Relating to Reactions of Polymers and to Functional Polymeric Materials

    Definitions of Terms Related to Polymer Blends, Composites, and Multiphase Polymeric Materials

    Terminology for Biorelated Polymers and Applications (IUPAC Recommendations 2012)

    Intrinsic Viscosity of Poly(ethylene glycol)

    International Union of Pure and Applied Chemistry

    Organic Name Reactions Useful in Biochemistry and Molecular Biology

    Brief Guide to the Nomenclature of Inorganic Chemistry

    Properties of Fluorescent Probes Commonly Used for Membrane Studies

    Chromatography

    Blotting Technologies

    Oxidation of Thiols

    Partial Volumes for Some Selected Compounds

    Appendix: Abbreviations and Acronyms

Handbook of Biochemistry and Molecular Biology

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    A Hardback by Roger L. Lundblad, Fiona Macdonald

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      View other formats and editions of Handbook of Biochemistry and Molecular Biology by Roger L. Lundblad

      Publisher: CRC Press
      Publication Date: 6/25/2018 12:00:00 AM
      ISBN13: 9781138033092, 978-1138033092
      ISBN10: 113803309X

      Description

      Book Synopsis

      Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web.

      Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature.

      New tables for this edition:

      • Chrom

        Table of Contents

        SECTION I: AMINO ACIDS, PEPTIDES, AND PROTEINS

        Properties of Amino Acids

        Data on the Naturally Occurring Amino Acids

        Coefficients of Solubility Equations of Certain Amino Acids in Water

        Heat Capacities, Absolute Entropies, and Entropies of Formation of Amino Acids and Related Compounds

        Heat of Combustion, Enthalpy, and Free Energy of Formation of Amino Acids and Related Compounds

        Solubilities of Amino Acids in Water at Various Temperatures

        Heats of Solution of Amino Acids in Aqueous Solution at 25°C

        Free Energies of Solution and Standard Free Energy of Formation of Amino Acids in Aqueous Solution at 25°C

        Far Ultraviolet Absorption Spectra of Amino Acids

        UV Absorption Characteristics of N-Acetyl Methyl Esters of the Aromatic Amino Acids, Cystine, and of N-Acetylcysteine

        Numerical Values of the Absorbances of the Aromatic Amino Acids in Acid, Neutral, and Alkaline Solutions

        Hydrophobicities of Amino Acids and Proteins

        Partial Volumes of Amino Acids

        Deamidation of Asparagine

        Michael Reactions of Proteins

        Molecular Weights of Proteins and Some Other Materials Including Sedimentation, Diffusion, and Frictional Coefficients and Partial Specific Volumes

        Molar Absorptivity and A1cm 1% Values for Proteins at Selected Wavelengths of the Ultraviolet and Visible Region

        Temperature Coefficients of Apparent Partial Specific Volumes of Proteins Expressed in ml/g/deg (dV/dT)

        Protein pK Values

        Intrinsic Viscosity of Proteins

        Infrared Spectra of Proteins

        Volume Changes for Some Macromolecule Association Reactions

        Assay of Solution Protein Concentration

        Spectrophotometric Determination of Protein Concentration in the Short-Wavelength Ultraviolet

        SECTION II: ENZYMES

        Turnover of Enzymes in Tissues

        Molecular Turnover of Cytochromes in Animals

        Matrix Metalloproteinases

        Proteases in the Interstitial Space

        Enzymes in Synthetic OrganicChemistry

        Therapeutic Enzymes

        Protease Inhibitors and Protease Inhibitor Cocktails

        SECTION III: LIPIDOMICS AND LIPIDOMES

        Evolution of the Classification and Nomenclature of Lipids

        A Brief Glossary for Lipidomics

        A Comprehensive Classification System for Lipids

        Properties of Fatty Acids and Their Methyl Esters

        Densities, Specific Volumes, and Temperature Coefficients of Fatty Acids from C8 to C12

        Composition and Properties of Common Oils and Fats

        Spectral Properties of Fatty Acids

        IR Active Bands of Phosphatidylethanolamines (PE)

        Concentration of Some Fatty Acids in Human Blood, Blood Plasma or Blood Serum

        Some Unusual Fatty Acid Structures

        SECTION IV: VITAMINS AND COE NZYMES

        Properties of Vitamins

        Biological Characteristics of Vitamins

        Vitamers

        Vitamin Names Discarded

        SECTION V: NUCLEIC ACIDS

        Some Definitions for Nucleic Acids

        UV Spectral Characteristics and Acidic Dissociation Constants of 280 Alkyl Bases, Nucleosides, and Nucleotides

        Ultraviolet Absorbance of Oligonucleotides Containing 2′-O-Methylpentose Residues

        Spectrophotometric Constants of Ribonucleotides

        Purines, Pyrimidines, Nucleosides, and Nucleotides: Physical Constants and Spectral Properties

        Chemical Modification of Nucleic Acids

        Polymerase Chain Reaction

        Gene Editing

        SECTION VI: GLYCOSCIENCE

        Nomenclature of Carbohydrates

        Chemical Modification of Carbohydrates

        Some Properties of Glycosaminoglycans

        Sugar Mimetics

        Intrinsic Viscosity of Polysaccharides

        SECTION VII: CHEMICAL BIOLOGY AND DRUG DESIGN

        Unnatural Amino Acids for Incorporation into Proteins

        Structures and Symbols for Synthetic Amino Acids Incorporated into Synthetic Polypeptides

        Properties of the α-Keto Acid Analogs of Amino Acids

        α,β-Unsaturated Amino Acids

        Amino Acid Antagonists

        Particle Diameter

        Weights of Cells and Cell Constituents

        Click Chemistry

        A Listing of Log P Values, Water Solubility, and Molecular Weight for Some Selected Chemicals

        SECTION VIII: PHYSICAL AND CHEMICAL DATA

        IUBMB-IUPAC Joint Commission on Biochemical Nomenclature (JCBN) Recommendations for Nomenclature and Tables in Biochemical Thermodynamics

        Standard Transformed Gibbs Energies of Formation for Biochemical Reactants

        Enthalpy, Entropy, and Free Energy Values for Biochemical Redox Reactions

        Oxidation-Reduction Potentials, Absorbance Bands, and Molar Absorbance of Compounds Used in Biochemical Studies

        Calorimetric ΔH Values Accompanying Conformational Changes of Macromolecules in Solution

        Free Energies of Hydrolysis and Decarboxylation

        Deci-Normal Solutions of Oxidation and Reduction Reagents

        Guidelines for Potentiometric Measurements in Suspensions Part A — The Suspension Effect

        Ionization Constants of Acids and Bases

        Guidelines for NMR Measurements for Determination of High and Low pKa Values

        Measurement and Interpretation of Electrokinetic Phenomena

        Measurement of pH Definition, Standards, and Procedures

        General Comments on Buffers

        List of Buffers

        Bronsted Acidities

        Buffer Solutions

        Amine Buffers Useful for Biological Research

        Preparation of Buffers for Use in Enzyme Studies

        Indicators for Volumetric Work and pH Determinations

        Acid and Base Indicators

        Specific Gravity of Liquids

        Properties of Some Solvents

        Chemicals Commonly Used in Biochemistry and Molecular Biology and their Properties

        Common Detergents Used in Biochemical Research

        Some Properties of Detergents and Surfactants Used in Biochemistry and Molecular Biology

        Some Biological Stains and Dyes

        Mordant Dyes

        Metal Chelating Agents

        Metallomics: Guidelines for Terminology and Critical Evaluation of Analytical Chemistry Approaches (IUPAC Technical Report)

        Water

        General Information on Spectroscopy

        Plastics

        Chemical and Physical Properties of Various Commercial Plastics

        Chemical Resistance of Plastics

        Generic Source-Based Nomenclature for Polymers

        Definitions of Terms Relating to Reactions of Polymers and to Functional Polymeric Materials

        Definitions of Terms Related to Polymer Blends, Composites, and Multiphase Polymeric Materials

        Terminology for Biorelated Polymers and Applications (IUPAC Recommendations 2012)

        Intrinsic Viscosity of Poly(ethylene glycol)

        International Union of Pure and Applied Chemistry

        Organic Name Reactions Useful in Biochemistry and Molecular Biology

        Brief Guide to the Nomenclature of Inorganic Chemistry

        Properties of Fluorescent Probes Commonly Used for Membrane Studies

        Chromatography

        Blotting Technologies

        Oxidation of Thiols

        Partial Volumes for Some Selected Compounds

        Appendix: Abbreviations and Acronyms

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