Description
Book SynopsisThe second edition of this textbook written for undergraduate students, graduate students and medical researchers, Genetics and Genomics in Medicine explains the science behind the uses of genetics and genomics in medicine today, and how it is being applied.
Maintaining the features that made the first edition so popular, this second edition has been thoroughly updated in line with the latest developments in the field. DNA technologies are explained, with emphasis on the modern techniques that are revolutionizing the use of genetic information in medicine and indicating the role of genetics in common diseases. Epigenetics and non-coding RNA are covered in-depth as are genetic approaches to treatment and prevention, including pharmacogenomics, genetic testing, and personalized medicine. A dedicated chapter charts the latest insights into the molecular basis of cancers, cancer genomics and novel approaches to cancer detection. Coverage of genetic testing at the level of
Trade Review
This excellent book is a must-have for any library, or anyone deeply interested in genetics and genomics in medicine. The writing is detailed yet easily understandable, and readers will come away much more knowledgeable on the
subject. This second edition is a much needed and exceptionally well-executed update to the original version.
- Mark F. Sanders, PhD, UC Davis College of Biological Sciences
Table of Contents1. Fundamentals of DNA, Chromosomes, and Cells
2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization
3. Principles Underlying Core DNA Technologies
4. Principles of Genetic Variation
5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies
6. Principles of Gene Regulation and Epigenetics
7. How Genetic Variation in DNA and Chromosomes Causes Disease
8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease
9. Genetic Approaches to Treating Disease
10. Cancer Genetics and Genomics
11. Genetic and Genomic Testing in Healthcare: Practical and Ethical Aspects
