Description
Book SynopsisWith the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease. Gene-profiling technologies and the concept of individualized medicine are leading to the development of drugs with enhanced specificity. This promises to lead to more effective treatment of diseases with reduced risk of side effects.
Gene Profiling in Drug Design provides insights from leaders in the pure sciences, biotechnology, and other arenas. It emphasizes the science that underpins gene profiling and drug development, and also includes clinical and ethical perspectives from experts in those fields. These explore the broadest health and social implications for this exciting field of science and discovery.
The book begins with a discussion of the future clinical impact of genetic diagnosis and gene-based drug therapies. Virally encoded MicroRNA is
Table of Contents
A Perspective on the Future Clinical Impact of Genetic Diagnosis and Gene-Based Drug Therapies for Patient Health. Virally Encoded MicroRNA (miRNA): Candidates for Gene Silencing. Development of Gene-Profile-Responsive Antisense Agents. Gene Profiles in Drug Development: Applications in Target Identification, Biomarker Discovery, and Compound Characterization. Gene Profiles and Cancer. RNA Viruses and RNA-Based Drugs: A Perfect Match for RNA Delivery and the Identification of Candidate Therapeutic Target Inflammatory Molecules. Ethical Considerations for a Genetic Future in Diagnosis and Drug Development.
