Description
Book SynopsisProvides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms.
Table of ContentsPreface.
Acknowledgements.
Abbreviations/Acronyms.
1. Biological Molecules.
2. An Introduction to Drugs and their Action.
3. An Introduction to Drug Discovery.
4. The SAR and QSAR Approaches to Drug Design.
5. Computer Aided Drug Design.
6. Combinatorial Chemistry.
7. Selected Examples of Drug Action at some Common Target Areas.
8. Pharmacokinetics.
9. Drug Metabolism.
10. An Introduction to Lead and Analogue Syntheses.
11. Drug Development and Production.
Appendix 1. Sickle-cell Anaemia.
Appendix 2. Bacteria.
Appendix 3. Cell Membranes.
Appendix 4. Receptors.
Appendix 5. Transfer through Membranes.
Appendix 6. Regression Analysis.
Appendix 7. Enzymes.
Answers to Questions.
Selected Further Reading.
Index.
