Description
Book SynopsisDesigned for upper-level undergraduate and graduate-level courses, Forensic Toxicology: Mechanisms and Pathology introduces toxicology concepts from a forensic perspective. The book provides an understanding of the mechanistic basis of the action of drugs and toxins, addressing their physiologic and pathologic consequences on the affected organ system. It is this essential connection of toxicology to physiology and biological systems that provides the basis for the toxicologist to understand the basis of behavioral effects of drugs, and for the forensic pathologist to determine cause of death when drugs may be involved.
The book gives an overview of organ system physiology and pathology, and the ways in which toxins and drugs affect those systems. Case histories, photographs of gross pathology, and photomicrographs further illustrate the processes and effects of toxic substances on the body. The book also focuses on technological advances in the field and includes cases
Table of Contents
PART I. Introduction. A Selected History of Forensic Toxicology. Toxicity and Toxidromes. Toxicokinetics. Biotransformation. Postmortem Toxicology. PART II. Neurotoxicology. Cardiac Toxicology. Hepatotoxicity. Kidney Toxicology. Pulmonary Toxicology. PART III. Alcohols: Ethanol, Methanol, and Related Compounds. Opiates and Opioids. Non-Opiate Sedative/Hypnotic Drugs. Sympathomimetic Amines: Amphetamines and Related Compounds. Hallucinogens, Psychedelics, and Cannabinoids. Cholinergic and Anticholinergic Toxins. Metals.