Description
Book SynopsisIn recent years, organo-fluorine chemistry has made a marked impacton the design and synthesis of a large variety of biologicallyactive molecules, such as steroids, carbohydrates, amines, aminoacids, peptides and other natural products. Naturally occurringamino acids play a pivotal role in living systems, and thereforesynthetic fluorine-containing amino acids have been of significantinterest to researchers working towards the understanding andmodification of physiological processes. Fluorine-containing AminoAcids:
* is the first volume devoted to the synthesis and properties offluorine-containing amino acids
* pays special attention to the preparation of enantiomericallypure acids (which are essential to the modern pharmaceuticalindustry)
* deals with a rapidly expanding field of research
* has been written by experienced researchers who are responsiblefor many developments in the field
* highlights the interdisciplinary nature of this topic
Fluorine-containing
Table of ContentsPartial table of contents:
Syntheses of Fluorine-Containing Amino Acids by Methods ofClassical Amino Acid Chemistry (V. Tolman).
Preparation of Fluorine-Containing Amino Acids by Methods ofOrganofluorine Chemistry (V. Kukhar).
Synthesis of Fluorine-Containing Amino Acids by Means ofHomogeneous Catalysis (I. Ojima & Q. Dong).
Synthesis of beta-Fluorine-Containing Amino Acids (N. Sewald &K. Burger).
Asymmetric Synthesis of Fluorine-Containing Amino Acids (V. Kukhar,et.
al).
Enzymatic Synthesis of Fluorine-Containing Amino Acids (Y.Matsumura & M. Urushihara).
Enzymatic Resolution of Racemic Fluorine-Containing Amino Acids (T.Miyazawa).
High-Performance Liquid Chromatography of Fluorine-Containing AminoAcids (S. Galushko).
Renin Inhibitors with Fluorine-Containing Amino Acid Derivatives(H. Sham).
Index.
