Description
Book SynopsisThe complete mapping of the horse genome sequence makes a significant contribution to understanding equine biology. This book provides a timely comprehensive overview of equine genomic research.
Trade Review“Equine Genomicsis an excellent text that compiles historical accomplishments in equine genetics and molecular biology, describes state-of-theart approaches to understanding the equine genome, and provides glimpses of where the field may go in the future . . . It is our responsibility to try to keep up, and I believe this book will help us do that.” (Journal of the American Veterinary Medical Association, 15 June 2014)
Table of ContentsContributors ix
Preface xi
Chapter 1 Defining the equine genome: The nuclear genome and the mitochondrial genome 1
Bhanu P. Chowdhary
Chapter 2 Genetic linkage maps 11
June Swinburne and Gabriella Lindgren
Chapter 3 Physical and comparative maps 49
Terje Raudsepp and Bhanu P. Chowdhary
Chapter 4 The Y-chromosome 73
Terje Raudsepp, Nandina Paria, and Bhanu P. Chowdhary
Chapter 5 Unexpected structural features of the equine major histocompatibility complex 93
Loren C. Skow and Candice L. Brinkmeyer-Langford
Chapter 6 Assembly and analysis of the equine genome sequence 103
Claire M. Wade
Chapter 7 Genomic tools and resources: Development and applications of an equine SNP genotyping array 113
Molly McCue and Jim Mickelson
Chapter 8 Functional genomics 125
Stephen J. Coleman, Michael J. Mienaltowski, and James N. MacLeod
Chapter 9 Coat color genomics 143
Samantha A. Brooks and Rebecca R. Bellone
Chapter 10 Genomics of skin disorders 155
Amy E. Young, Stephen D. White, and Danika L. Bannasvch
Chapter 11 Genomics of muscle disorders 171
James R. Mickelson, Stephanie J. Valberg, Carrie J. Finno, and Molly E. McCue
Chapter 12 Genomics of skeletal disorders 187
Ottmar Distl
Chapter 13 Genomics of reproduction and fertility 199
Terje Raudsepp, Pranab J. Das and Bhanu P. Chowdhary
Chapter 14 Genetics of equine neurologic disease 217
Carrie J. Finno and Monica Aleman
Chapter 15 Molecular genetic testing and karyotyping in the horse 241
M. C. T. Penedo and Terje Raudsepp
Chapter 16 Genomics of laminitis 255
Jim K. Belknap
Chapter 17 Genomics of performance 265
Emmeline W. Hill, Lisa M. Katz, and David E. MacHugh
Chapter 18 Genomics of the circadian clock 285
Barbara A. Murphy
Chapter 19 Mitochondrial genome: Clues about the evolution of extant equids and genomic diversity of horse breeds 311
Cynthia C. Steiner, Kateryna D. Makova, and Oliver A. Ryder
Index 323
