Description

Book Synopsis
Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism.

Table of Contents

Preface vii

Author’s Review ix

Part I 1 Characteristics of Enzymes 3

2 Self-Assembly of Polymers 17

3 Beginnings of Equations 27

4 Metabolite Distribution Systems 37

5 Modification of Enzymatic Activity 51

6 Modification of Metabolite Flow Through Metabolic Pathways 67

7 Which is the Real Substrate? 75

8 Non-Quasi-Equilibrium Assumptions 79

9 Underlying Attributes of Assessing Enzymatic Activities 85

Part II 10 Breakdown of the Michaelis–Menten Equation (or Complex Enzyme Mechanisms) 97

11 Rate Equation Derivation by the King–Altman Method: Two Substrates and Two Products 117

12 Modification of Enzyme Mechanisms: The Next Generation 141

13 What Are These “Rate Constants” We Have Been Dealing With? 151

Index 165

Enzyme Regulation in Metabolic Pathways

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      Description

      Book Synopsis
      Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism.

      Table of Contents

      Preface vii

      Author’s Review ix

      Part I 1 Characteristics of Enzymes 3

      2 Self-Assembly of Polymers 17

      3 Beginnings of Equations 27

      4 Metabolite Distribution Systems 37

      5 Modification of Enzymatic Activity 51

      6 Modification of Metabolite Flow Through Metabolic Pathways 67

      7 Which is the Real Substrate? 75

      8 Non-Quasi-Equilibrium Assumptions 79

      9 Underlying Attributes of Assessing Enzymatic Activities 85

      Part II 10 Breakdown of the Michaelis–Menten Equation (or Complex Enzyme Mechanisms) 97

      11 Rate Equation Derivation by the King–Altman Method: Two Substrates and Two Products 117

      12 Modification of Enzyme Mechanisms: The Next Generation 141

      13 What Are These “Rate Constants” We Have Been Dealing With? 151

      Index 165

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