Description
Book SynopsisThe interfacing of man-made electronics with redox proteins and enzymes not only tells us a great deal about the levels of sophistication active in biology, but also paves the way to using it in derived sensory devices. Some of these have already had a profound impact on both clinical diagnostics and the quality of life enjoyed by those unfortunate enough to live with disease. Though much remains to be learnt about controlling and optimising these interfacial interactions, their potential uses are, if anything, growing. Written by leaders in the field, this is the only book to focus on the generation of biosensing interfaces with analyses and control at the molecular level. Some of these are enzyme based, others associated with the generation of surfaces for protein-protein recognition. Summaries of state-of-the-art investigations into the interfacing of structurally complex molecular species with electrode surfaces are included along with their design, analysis and potential applicati
Trade Review"chapters are of uniformly good quality and provide a critical assessment of the recent literature...""This volume has a lot to offer in fundamental chemistry with regard to its title.""I highly recommend this volume to the many who are working doggedly in this field..." * JACS, Vol 132 No 4, 2010, Peter Kissinger *
Table of ContentsChapter 1: The Mononuclear Molybdoenzymes: potential applications in redox enzyme biosensors; Chapter 2: Scanning Probe Analyses at the Bioelectronic Interface; Chapter 3: Electrical Interfacing of Redox Enzymes with Electrodes by the Surface Reconstitution of Apo-Enzymes; Chapter 4: Single-wall carbon nanotube forests in biosensors; Chapter 5: Energizing redox enzymes through substrate surface preparation and wiring; Chapter 6: Cytochromes P450s: Tayloring a class of enzymes for biosensing; Chapter 7: Label free field effect protein sensing; Chapter 8: Biological and Clinical Applications of Protein Biosensors
