Description
Book SynopsisThe literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphisms in cytokine genes. It discusses haplotype structures and linkage disequilibrium patterns in cytokine gene loci; functional biological effects of polymorphisms; and genetic associations with disease. The book documents polymorphisms in the most important cytokine genes, or gene clusters, and their biological and genetic effects in a multitude of distinct multifactorial conditions.
Unique to this book are the disease-centered chapters examining the role of cytokine gene polymorphisms in a multitude of multifactorial conditions. The conditions include autoimmune or chronic inflammatory diseases, cardiovascular disease, infectious di
Trade Review
"As this volume so capably demonstrates, genetic variation in cytokines, the messengers of the immune system, and their receptors is now recognized as playing an important role in disease susceptibility and outcome...This book is a timely anthology of knowledge, techniques as well as informed speculation…The chapters in this book represent an excellent and timely means of addressing questions related to the study of cytokine gene polymorphisms and will serve as an important reference work.."
- From the foreword by Grant Gallagher and Michael F. Seldin, Editors, "Genes and Immunity", March 2006
Table of ContentsGeneral Concepts. Cytokine Gene Polymorphisms. Polymorphic Cytokine Networks in Multifactorial Conditions.
