Description

Book Synopsis
The book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of cells, genetic instability, and angiogenesis. The book also discusses the use of mathematical models for the analysis of therapeutic approaches such as chemotherapy, immunotherapy, and the use of oncolytic viruses.

Table of Contents
Cancer and Somatic Evolution Mathematical Modeling of Tumorigenesis Cancer Initiation: One-Hit and Two-Hit Stochastic Models Microsatellite and Chromosomal Istability in Sporadic and Familial Cancers Cellular Origins of Cancer Costs and Benefits of Chromosomal Instability DNA Damage and Genetic Instability Tissue Aging and the Development of Cancer Basic Models of Tumor Inhibition and Promotion Mechanisms of Tumor Neovascularization Cancer and Immune Responses Therapeutic Approaches: Viruses as Anti-Tumor Weapons

Computational Biology Of Cancer: Lecture Notes

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    A Hardback by Dominik Wodarz, Natalia Komarova

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      View other formats and editions of Computational Biology Of Cancer: Lecture Notes by Dominik Wodarz

      Publisher: World Scientific Publishing Co Pte Ltd
      Publication Date: Publication Date: 26/01/2005
      ISBN13: 9789812560278, 978-9812560278
      ISBN10: 9812560270

      Description

      Book Synopsis
      The book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of cells, genetic instability, and angiogenesis. The book also discusses the use of mathematical models for the analysis of therapeutic approaches such as chemotherapy, immunotherapy, and the use of oncolytic viruses.

      Table of Contents
      Cancer and Somatic Evolution Mathematical Modeling of Tumorigenesis Cancer Initiation: One-Hit and Two-Hit Stochastic Models Microsatellite and Chromosomal Istability in Sporadic and Familial Cancers Cellular Origins of Cancer Costs and Benefits of Chromosomal Instability DNA Damage and Genetic Instability Tissue Aging and the Development of Cancer Basic Models of Tumor Inhibition and Promotion Mechanisms of Tumor Neovascularization Cancer and Immune Responses Therapeutic Approaches: Viruses as Anti-Tumor Weapons

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