Description
Book SynopsisOrganic reactions in water have proven a useful synthetic tool, and provide cost-efficient, safe, and environmentally friendly alternatives to organic-solvent based reactions. This field has been greatly expanded over the last decade, and currently there are many diverse applications in both industry and academic laboratories.
Trade Review"As it is a conference report, the book is clearly intended for specialists in the field." (
Angewandte Chemie, 2008-47/11)
"…a testament to the enormous expansion in the field of water-based chemistry, and compiling it in a single volume is very useful." (Journal of the American Chemical Society, December 26, 2007)
"Advanced students and research and development chemists with an interest in green chemistry are highly recommended to purchase this book." (Organic Chemistry Portal, January 2008)
"Diese Aktualisierung einer klassischen Monographie fasst die bedeutenden Fortschritte auf dem Gebiet organischer Reaktionen in wassriger Phase in den letzten Jahren hervorragend zusammen."
Angewandte Chemie
2008-120/11
Table of ContentsPREFACE TO THE SECOND EDITION. 1. INTRODUCTION.
1.1 The Structure and Forms of Water.
1.2 Properties of Water.
1.3 Solvation.
1.4 Hydrophobic Effect.
1.5 Salt Effect.
1.6 Water Under Extreme Conditions.
References.
2. ALKANES.
2.1 Oxygenation of Alkanes.
2.2 Halogenation of Alkanes.
2.3 Formation of Carbon–Carbon Bonds.
2.4 D/H Exchange of Alkanes in Water.
References.
3. ALKENES.
3.1 Reduction.
3.2 Electrophilic Additions.
3.3 Radical Reactions of Alkenes.
3.4 Carbene Reactions.
3.5 Alkene Isomerization.
3.6 Transition-Metal Catalyzed C–C Formation Reactions.
3.7 Olefin Metathesis.
3.8 Reaction of Allylic C–H Bond.
4. ALKYNES.
4.1 Reaction of Terminal Alkynes.
4.2 Additions of C≡C bonds.
4.3 Transition-Metal Catalyzed Cycloadditions.
4.4 Other Reactions.
References.
5. ALCOHOLS, PHENOLS, ETHERS, THIOLS, AND THIOETHERS.
5.1 Oxidation of Alcohols.
5.2 Substitutions/Elimination.
5.3 Addition of Alcohols, Phenols, and Thiols to Alkene and Alkyne Bonds.
5.4 Addition of Alcohols to C=O Bonds: Esterification and Acetal Formations.
5.5 Reaction of Ethers and Cyclic Ethers.
5.6 Reaction of Sulfur Compounds.
6. ORGANIC HALIDES.
6.1 General.
6.2 Reduction.
6.3 Elimination Reactions.
6.4 Nucleophilic Substitutions.
6.5 Reductive Coupling.
6.6 Carbonylation of Organic Halides.
6.7 Transition-Metal Catalyzed Coupling Reactions.
References.
7. AROMATIC COMPOUNDS.
7.1 General.
7.2 Substitution Reactions.
7.3 Oxidation Reactions.
7.4 Reductions.
References.
8. ALDEHDYE AND KETONES.
8.1 Reduction.
8.2 Oxidation.
8.3 Nucleophilic Addition: C–C Bond Formation.
8.4 Pinacol Coupling.
8.5 Other Reactions (Halogenation and Oxidation of α-H).
References.
9. CARBOXYLIC ACIDS AND DERIVATIVES.
9.1 General.
9.2 Carboxylic Acids.
9.3 Carboxylic Acid Derivatives.
References.
10. CONJUGATED CARBONYL COMPOUNDS.
10.1 Reduction.
10.2 Epoxidation, Dihydroxylation, Hydroxyamination.
10.3 Conjugate Addition: Heteroatom.
10.4 C–C Bond Formation.
10.5 Other Reactions.
References.
11. NITROGEN COMPOUNDS.
11.1 Amines.
11.2 Imines.
11.3 Diazo Compounds.
11.4 Azides.
11.5 Nitro Compounds.
References.
12. PERICYCLIC REACTIONS.
12.1 Introduction.
12.2 Diels-Alder Reactions.
12.3 Sigmatropic Rearrangements.
12.4 Photochemical Cycloaddition Reactions.
References.
INDEX.
