Description
Book SynopsisThis new edition provides clinicians and trainees with guidance on the latest clinical research techniques and publishing in medical literature.
Divided into six sections, the book begins with an overview of research and evidence-based medicine, then discusses the strengths and limitations of specific research designs including randomised controlled trials, cohort studies, case control studies and much more.
The following sections cover reporting guidelines, writing a good research paper, sample size calculations, subgroup analyses and associated topics such as research ethics and patient consent.
The second edition has been fully revised and expanded and includes new advanced content. Clinical images and figures further enhance the comprehensive text.
Key points
- New edition providing guidance on latest clinical research techniques and publishing in medical literature
- Fully revised and expanded content with new advanced topics
- Internationally recognised author team
- Previous edition (9788184488906) published in 2010
Table of ContentsSection 1: The Basics
- The Origins of Evidence-based Medicine
- Why do We Need Evidence-based Medicine
- Tips to becoming an Evidence-based Clinician
- Quality of Evidence—has it Improved?
Section 2: Choosing the Right Study Design
- Levels of Evidence—A Quick Guide
- Level 1 Evidence—Randomized Controlled Trials
- Level 2 Evidence—Prospective Cohort Studies
- Level 3 Evidence—Case-control Studies
- Level 4 Evidence—Clinical Case Series
- Level 5 Evidence—Surveys
Section 3: Special Designs and Topics
- The Basics of Systematic Reviews and Meta-analysis
- The Basics of Economic Evaluation
- The Basics of a Diagnostic Test Study
- The Basics of Reliability
- Quick Guide to Assess Risk of Bias in Randomized Controlled Trials
- GRADE—Understanding Grades of Healthcare Recommendations
Section 4: The Research Protocol
- First Things First—The Research Proposal
- Choosing the Outcome—A Primer
- Common Quality of Life and Health Utility Outcome Tools
- An Introduction to Sample Size
- Estimating an Appropriate Sample Size—Advanced Concepts, Formulae and Examples
- Planning your Analysis—Keep it Simple
- What are Subgroup Analyses and How Should You Interpret Them?
Section 5: Doing Research
- Study Roles—Who does What?
- Research Ethics Approval—A must Before any Clinical Trial
- Why do we Need Patient Consent? Designing a Good Consent Form
- Collecting Data—It all Begins with a Good Data Form
Section 6: Getting the Word Out— Presentation and Publication
- Creating an Impactful Slide Presentation
- Writing a Good Clinical Research Paper
- Making Sense of Reporting Guidelines
- Submitting a Paper for Publication—A Guide to Success
- Knowledge Translation 101—Maximizing Impact
Glossary
Index
