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Book Synopsis

Chromothripsis.- Chromoanasynthesis.- Chromoplexy.- Chromoanagenesis and Beyond: Catastrophic Events Shaping the Genome.- Performing SABER-FISH on Chromosome Spreads in Fixed Tissue Culture Cells and in Tissues.- Genomic Detection and Delineation of Chromoanasynthesis by Mate-Pair Sequencing.- Detection of Complex Genomic Rearrangements Using Short-Read Whole Genome Sequencing in C. elegans.- Hybrid Sequencing Characterization of Complex Chromosomal Rearrangements.- Combination of Long-Read Sequencing and Hi-C Technology to Identify Chromoanagenesis Events in Cancer.- Identification and Characterization of Chromothripsis by Optical Genome Mapping.- Exploring Chromoanagenesis with DAFCA (Dam Assisted Fluorescent Tagging of Chromatin Accessibility): Integrating Chromatin Accessibility and Optical Genome Mapping for Enhanced Structural Variant Detection.- Leveraging Hi-C Data to Detect Chromosomal Reorganizations.- Chromoanagenesis Detection in Chronic Lymphocytic Leukemia.- Application and Prospects of Long Read Sequencers for Preimplantation Genetic Testing for Structural Rearrangements.- Visual Inspection of Sequencing Data for Diagnosis: Practical Guide to Structural Variant Analysis Using Integrative Genomics Viewer (IGV).- Artificial Intelligence and Chromothripsis.- Machine Learning for Detecting and Analyzing Chromoanagenesis Events.- ISCN and Chromoanagenesis.- Structural and Mechanistic Diversity of Constitutional Chromoanagenesis.- Chromoanagenesis in Multiple Myeloma: A Comprehensive Overview.- Origin and Fate of Micronuclei on the Road to Chromoanagenesis.- The Fate of Micronuclei.- Transgenerational Tracking of Chromosomes from Micronuclei.- Investigating Nuclear Envelope Assembly on Mis-Segregated Chromosomes.- Transcription-Replication Conflicts and Incomplete Replication as a Cause of Micronuclei-Driven Chromoanagenesis.- DNA Damage, Telomere and Centromere Dysfunction in Chromothripsis Rearrangements.- Incomplete Trisomic Rescue by Chromothripsis Leads to Small Supernumerary Marker Chromosomes.- Oligopaint FISH to Study Chromosomal Architecture and Structural Variations.- Single Molecule Studies with AFM and High-Speed AFM: From Nucleosomes to Chromosomes.- Multifocal Genomic Reconstruction Leading to Germline Structural Variants.- Sperm DNA Fragmentation as a Marker of Chromoanagenesis Occurrence during Spermatogenesis.- Isolation of Germ Cell Populations from Mouse Testis by Flow Cytometry.- The Chromatin Configuration Promotes Constitutional Chromosomal Rearrangements in Post-Meiotic Sperm.- Recql5-Deficient Mice as a Model for Studying Chromoanagenesis Phenomena.- Computational Modeling of Chromoanagenesis- or Chromothripsis-Induced SNPs in Anti-Apoptotic Genes: Their Impact on Protein Structure and Function.- Chromosomal Instability and Chromoanagenesis as Forces for Genomic Evolution.- The Evolutionary Potential of Chromoanagenesis.

Chromoanagenesis

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    A Hardback by Franck Pellestor

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      View other formats and editions of Chromoanagenesis by Franck Pellestor

      Publisher: Humana
      Publication Date: 30/09/2025
      ISBN13: 9781071647493, 978-1071647493
      ISBN10:
      Also in:
      Genetics (non-medical)

      Description

      Book Synopsis

      Chromothripsis.- Chromoanasynthesis.- Chromoplexy.- Chromoanagenesis and Beyond: Catastrophic Events Shaping the Genome.- Performing SABER-FISH on Chromosome Spreads in Fixed Tissue Culture Cells and in Tissues.- Genomic Detection and Delineation of Chromoanasynthesis by Mate-Pair Sequencing.- Detection of Complex Genomic Rearrangements Using Short-Read Whole Genome Sequencing in C. elegans.- Hybrid Sequencing Characterization of Complex Chromosomal Rearrangements.- Combination of Long-Read Sequencing and Hi-C Technology to Identify Chromoanagenesis Events in Cancer.- Identification and Characterization of Chromothripsis by Optical Genome Mapping.- Exploring Chromoanagenesis with DAFCA (Dam Assisted Fluorescent Tagging of Chromatin Accessibility): Integrating Chromatin Accessibility and Optical Genome Mapping for Enhanced Structural Variant Detection.- Leveraging Hi-C Data to Detect Chromosomal Reorganizations.- Chromoanagenesis Detection in Chronic Lymphocytic Leukemia.- Application and Prospects of Long Read Sequencers for Preimplantation Genetic Testing for Structural Rearrangements.- Visual Inspection of Sequencing Data for Diagnosis: Practical Guide to Structural Variant Analysis Using Integrative Genomics Viewer (IGV).- Artificial Intelligence and Chromothripsis.- Machine Learning for Detecting and Analyzing Chromoanagenesis Events.- ISCN and Chromoanagenesis.- Structural and Mechanistic Diversity of Constitutional Chromoanagenesis.- Chromoanagenesis in Multiple Myeloma: A Comprehensive Overview.- Origin and Fate of Micronuclei on the Road to Chromoanagenesis.- The Fate of Micronuclei.- Transgenerational Tracking of Chromosomes from Micronuclei.- Investigating Nuclear Envelope Assembly on Mis-Segregated Chromosomes.- Transcription-Replication Conflicts and Incomplete Replication as a Cause of Micronuclei-Driven Chromoanagenesis.- DNA Damage, Telomere and Centromere Dysfunction in Chromothripsis Rearrangements.- Incomplete Trisomic Rescue by Chromothripsis Leads to Small Supernumerary Marker Chromosomes.- Oligopaint FISH to Study Chromosomal Architecture and Structural Variations.- Single Molecule Studies with AFM and High-Speed AFM: From Nucleosomes to Chromosomes.- Multifocal Genomic Reconstruction Leading to Germline Structural Variants.- Sperm DNA Fragmentation as a Marker of Chromoanagenesis Occurrence during Spermatogenesis.- Isolation of Germ Cell Populations from Mouse Testis by Flow Cytometry.- The Chromatin Configuration Promotes Constitutional Chromosomal Rearrangements in Post-Meiotic Sperm.- Recql5-Deficient Mice as a Model for Studying Chromoanagenesis Phenomena.- Computational Modeling of Chromoanagenesis- or Chromothripsis-Induced SNPs in Anti-Apoptotic Genes: Their Impact on Protein Structure and Function.- Chromosomal Instability and Chromoanagenesis as Forces for Genomic Evolution.- The Evolutionary Potential of Chromoanagenesis.

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