Description
Book SynopsisFeaturing contributions from researchers in the diverse fields of neuroinjury, myocardial injury, diabetes, shock, and inflammation, this text examines the status of the field of poly (ADP-ribose) polymerase (PARP) and cell death. It also explores PARP and apoptosis, PARP and DNA repair, as well as PARP and regulation of gene expression.
Table of ContentsPreface. Cell Death by Energy Depletion: Discovery and Early Developments. Oxidative Stress and PARS Activation. Nitrosative Stress and PARS Acitvation. PARS in Regulating Cell Necrosis and Apoptosis. PARS in Mediating Neuronal Injury in Stroke and Neurotrauma. PARS in Mediating Chronic Neurodegeneration. PARS Activation and Myocardial Reperfusion Injury. Role of PARS Activation in the Pathophysiology of Endotoxic and Hemorrhagic Shock. Role of PARS Activation in Diabetes. PARS Activation and Arthritas. PARS Activation and Inflammatory Bowel Disease. PARS in Regulating Macrophage Activation and Gene Expression. Pharmacological Inhibitors of PARS.
