Description
Book SynopsisThis book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.
Table of ContentsPREFACE xi
FOREWORD xiii
CONTRIBUTORS xv
I NEW MATERIALS AND TECHNOLOGIES: SUPPORTED CATALYSTS, SUPPORTS, SELFSUPPORTED CATALYSTS, CHIRAL IONIC LIQUID, SUPERCRITICAL FLUIDS, FLOW REACTORS, AND MICROWAVES 1
1 RECYCLABLE STEREOSELECTIVE CATALYSTS 3
Carlos M. Monteiro, Alexandre F. Trindade, Pedro M. P. Gois, and Carlos A. M. Afonso
2 RECYCLABLE ORGANOCATALYSTS IN ASYMMETRIC REACTIONS 83
Michelangelo Gruttadauria, Francesco Giacalone, and Renato Noto
3 SYNTHESIS AND CHARACTERIZATION OF SUPPORTED CHIRAL CATALYSTS 177
Carmela Aprile, Hermenegildo Garcia, and Paolo P. Pescarmona
4 SYNTHESIS OF CHIRAL CATALYSTS SUPPORTED ON ORGANIC POLYMERS 209
Tor Erik Kristensen and Tore Hansen
5 SELF-SUPPORTED CHIRAL CATALYSTS 257
Hongchao Guo and Kuiling Ding
6 CATALYSIS WITH CHIRALLY MODIFIED METAL SURFACES: SCOPE AND MECHANISMS 291
Angelo Vargas, Cecilia Mondelli, and Alfons Baiker
7 CHIRAL IONIC LIQUIDS FOR ASYMMETRIC REACTIONS 323
Annie-Claude Gaumont, Yves Génisson, Frédéric Guillen, Viacheslav Zgonnik, and Jean-Christophe Plaquevent
8 ASYMMETRIC REACTIONS IN FLOW REACTORS 345
Munawwer Rasheed, Simon C. Elmore, and Thomas Wirth
9 ASYMMETRIC CATALYTIC SYNTHESIS IN SUPERCRITICAL FLUIDS 373
Tomoko Matsuda
10 MICROWAVE-ASSISTED TRANSITION METAL-CATALYZED ASYMMETRIC SYNTHESIS 391
Luke R. Odell and Mats Larhed
II RECENT ADVANCES IN ORGANOCATALYTIC, ENZYMATIC, AND METAL-BASED MEDIATED ASYMMETRIC SYNTHESIS 413
11 RECENT ADVANCES ON STEREOSELECTIVE ORGANOCATALYTIC REACTIONS. ORGANOCATALYTIC SYNTHESIS OF NATURAL PRODUCTS AND DRUGS 415
Monika Raj and Vinod K. Singh
12 RECENT ADVANCES IN BIOCATALYSIS APPLIED TO ORGANIC SYNTHESIS 491
Gonzalo De Gonzalo, Iván Lavandera, and Vicente Gotor
13 PEPTIDES FOR ASYMMETRIC CATALYSIS 529
Matthias Freund and Svetlana B. Tsogoeva
14 SILICATE-MEDIATED STEREOSELECTIVE REACTIONS CATALYZED BY CHIRAL LEWIS BASES 579
Maurizio Benaglia, Stefania Guizzetti, and Sergio Rossi
15 RECENT ADVANCES IN THE METAL-CATALYZED STEREOSELECTIVE SYNTHESIS OF BIOLOGICALLY ACTIVE MOLECULES 625
Catalina Ferrer, Xavier Verdaguer, and Antoni Riera
16 STEREOSELECTIVE NITROGEN HETEROCYCLE SYNTHESIS MEDIATED BY CHIRAL METAL CATALYSTS 671
Sherry R. Chemler
INDEX 689
