Description
Book SynopsisWith the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. This invaluable volume contains analysed, evaluated and distilled information on the latest in carbohydrate research. The discovery and synthesis of novel carbohydrates and mimetics with diverse applications continues to be a major challenge for carbohydrate chemists. The understanding of the structure and function of carbohydrates and glycoconjugates remains vital in medicine and molecular biology. This volume collates modern carbohydrate research from theory to application and demonstrates the importance of carbohydrates in new lead generation. It is of benefit to any researcher who wishes to learn about the latest developments in the carbohydrate field.
Table of ContentsContemporary glycoconjugation chemistry; Advances in applications of NMR methods to uncover the conformation and recognition features of glycans; Recent advances in Kdo-glycoside synthesis; Predictable and highly efficient preparation of carbohydrate-based vaccines: Squaric acid chemistry is the way to go; Synthetic Approaches to Cyclodextrins and Their Analogues; Bacterial lipopolysaccharides covalently bound to hopanoids: key molecules that favour the life of Bradyrhizobia in stressful environments; Giant dsDNA viruses taste for sugars; Glycosteroids: a specific type of glycolipids with self assembly properties; Recent examples of novel synthetic approaches to diverse amino-sugars; FimH Antagonists – Solubility vs. Oral Availability; Ferrier rearrangement. An update on recent developments; Recent advances in the synthesis of iminosugars. An insight into the cascade addition of Grignard reagents to halonitriles/cyclization;
