Description
Book SynopsisCapillary electrophoresis–mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In this book, the unique features of CE-MS for metabolomics studies are highlighted including CE separation modes, capillary coatings and practical aspects of CE-MS coupling alongside a comprehensive overview of recent technological developments and applications. CE-MS can be considered a relatively new technique in the field of metabolomics and it is therefore important to inform the scientific community about the possibilities of advanced CE-MS approaches for metabolomics studies. This book outlines the potential of this technique for researchers working in metabolomics, bioanalytics and biomarker analysis.
Table of ContentsCapillary Electrophoresis–Mass Spectrometry for Metabolomics - From Metabolite Analysis to Metabolic Profiling; CE-MS Workflows for Metabolomics: A Focus on Sample Preparation; Capillary Electrophoresis–Mass Spectrometry Using Non-covalently Coated Capillaries for Metabolic Profiling of Biological Samples; Capillary Electrophoresis–Mass Spectrometry for Metabolomics Using New Interfacing Designs; Stacking or On-line Sample Concentration in CE-MS for Metabolomics; On-line Solid-phase Extraction Capillary Electrophoresis–Mass Spectrometry and Data Analysis Approaches for Metabolomics; CE-MS for Anionic and Cationic Metabolic Profiling: System Optimization and Applications; CE-MS for Metabolomics: A Comparison with Other Techniques; Potential of CE-MS for Chiral Metabolic Profiling; Single-cell Metabolomics with Capillary Electrophoresis–Mass Spectrometry; Capillary Electrophoresis-Mass Spectrometry for Lipid Analysis; Multisegment Injection–Capillary Electrophoresis–Mass Spectrometry: A Robust Platform for High Throughput Metabolite Profiling with Quality Assurance; Subject Index
