Description

Book Synopsis

Cancer cells exist in an ever-changing âœecologyâ and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.

Key Features

  • Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated.
  • Offers insights from leading scholars in cancer biology, ecolo

Cancer through the Lens of Evolution and Ecology

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Order before 4pm today for delivery by Sat 13 Dec 2025.

A Paperback by Jason A. Somarelli

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    View other formats and editions of Cancer through the Lens of Evolution and Ecology by Jason A. Somarelli

    Publisher: CRC Press
    Publication Date: 5/29/2024
    ISBN13: 9781032310770, 978-1032310770
    ISBN10: 1032310774
    Also in:
    Science & Nature Cellular biology (cytology)

    Description

    Book Synopsis

    Cancer cells exist in an ever-changing âœecologyâ and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.

    Key Features

    • Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated.
    • Offers insights from leading scholars in cancer biology, ecolo

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