Description
Book SynopsisThis updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant and cellular therapy patients.
Spanning the timeline from the initial consultation throughout the transplant process, this handbook begins by providing a general overview of stem cell transplantation and goes on to outline disease-specific indications for stem cell transplantation. It then focuses on transplant complications and ongoing care, and finally explores cellular therapies for hematologic malignancies.
Comprehensive and easy-to-use, Blood and Marrow Transplant Handbook: Comprehensive Guide for Patient Care, Third Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers as well as residents, fellows, and other trainees who care for patients who undergo transplant and immune effector cell therapy.
Table of ContentsOverview of Hematopoietic Stem Cell Transplantation & Cellular Therapy
The Business of Cellular Therapy and Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Sources and Donor Selection
Pre-transplant Assessment for Hematopoietic Stem Cell Transplantation Recipients and Donors
Social Work: Evaluation and Social Supports
Conditioning Regimens
Nutrition
Physical and Occupational Therapy
Adolescent and Young Adult Concerns
Infection Prevention and Prophylaxis
Graft-versus-Host Disease (GvHD) Prophylaxis
Transfusion Medicine
Anticoagulation and Antiplatelet Guidelines
Engraftment
Acute Myeloid Leukemia and Allogeneic Hematopoietic Stem Cell Transplant
Acute Lymphoblastic Leukemia
Hodgkin Lymphoma and non-Hodgkin Lymphoma
Multiple Myeloma
HSCT for Germ Cell Tumors
Hematopoietic Stem Cell Transplant for Myelofibrosis
Chronic Myeloid Leukemia
Chronic Lymphocytic Leukemia
Hematopoietic Stem Cell Transplant for Severe Aplastic Anemia
Inherited Disorders
Hematopoietic Cell Transplant and Cellular Therapies for Sickle Cell Disease
Radiology Pearls for the Transplant Provider
Acute Graft-Versus-Host Disease (GvHD)
Chronic Graft-versus-Host Disease
Immune Reconstitution
Infectious Complications
Oral Complications
Gastrointestinal Complications
Pulmonary Complications
Cardiovascular Complications
Kidney Disease in Hematopoietic Stem Cell Transplantation
Neurological Complications
Endocrine Complications following Hematopoietic Stem Cell Transplantation
Thrombotic Microangiopathies
Women’s Health Care
Men’s Health for Bone Marrow Transplant Patients
Psychiatric Complications
Graft Failure
Second Primary Malignancies
Relapse after Hematopoietic Stem Cell Transplantation
Safe Pain Management with Opioids in Post-Transplant Patients
Complementary Medicine: Acupuncture
Complementary Medicine
Complementary Medicine: Cannabinoids and the Hematopoietic Stem Cell Transplant (HSCT) Recipient
Management of Neurocognitive Effects and Fatigue During and After Stem Cell Transplant
Palliative Care
Long-Term Follow Up and Survivorship
CAR T Cells for Hematologic Malignancies
Natural Killer Cell Therapy in Allogeneic Stem Cell Transplant
Mesenchymal stromal cells: Impact on hematopoietic cell transplantation
T cell Therapeutics: Donor Lymphocyte Infusion, Cytotoxic T Lymphocyte Infusion and Other Non-CAR T cell Therapies
Dendritic Cell Vaccines
BiTEs, DARTs and Peri-Transplant Minimal Residual Disease
CAR T Toxicity Management: Cytokine Release Syndrome and Neurotoxicity
Molecular testing for post-transplant surveillance
Management of Immune Compromised Transplant and Immune Effector Cell Treated Patients in the Setting of the COVID-19 Viral Pandemic: the OHSU Experience
Appendix 1: The Vocabulary of Transplant
Appendix 2: Procedure - Bone Marrow Aspirate and Biopsy
Appendix 3: Procedure - Lumbar Puncture
Appendix 4: Procedure - Ommaya reservoir tap
Appendix 5: Procedure - Skin Biopsy
Appendix 6: OHSU Food Safe Diet
Appendix 7: OHSU Low Bacteria Diet
Appendix 8: OHSU’s Graft-versus-host disease diet
Appendix 9: OHSU vaccine guidelines
Appendix 10: OHSU Donor and stem cell source selection in allogeneic hematopoietic progenitor cell transplantation
