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Book Synopsis
This book presents the basic results on studies of the interaction of anti-cancer Actinomycin antibiotics with DNA. It focuses on interactions of heterocyclic anti-tumour antibiotics (Actinomycins, as typical example) with DNA, poly-nucleotides, oligonucleotides, and aggregates of purines, using spectroscopic methods. Experimental data, various models of structures of the complexes and their physical and chemical properties are described, and possible approaches for delivery of heterocyclic antibiotics to DNA are also discussed.

Biophysics of DNA-Antibiotic Complexes

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    A Hardback by Nikolai Vekshin

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      Publisher: Nova Science Publishers Inc
      Publication Date: Publication Date: 04/05/2011
      ISBN13: 9781617611995, 978-1617611995
      ISBN10: 1617611999

      Description

      Book Synopsis
      This book presents the basic results on studies of the interaction of anti-cancer Actinomycin antibiotics with DNA. It focuses on interactions of heterocyclic anti-tumour antibiotics (Actinomycins, as typical example) with DNA, poly-nucleotides, oligonucleotides, and aggregates of purines, using spectroscopic methods. Experimental data, various models of structures of the complexes and their physical and chemical properties are described, and possible approaches for delivery of heterocyclic antibiotics to DNA are also discussed.

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