Description
Book SynopsisIn the post-genomic world, advances in the comprehension of cell behaviour will depend upon scientists deciphering the molecular basis of interactions between proteins and membranes. Bringing together contributions from chemists, biologists and physicists, Biophysical Chemistry: Membranes and Proteins demonstrates how multidisciplinary teams can gain insights into understanding complex biological systems. This book reflects both the scope and the interdisciplinary nature of the field, with topics including: modelling of biological systems; membrane structure and interactions; probing biomolecules; and channels and receptors. Full of stimulating articles and opinions, readers from academia and industry will welcome the wide range of coverage and the state-of-the-art science.
Trade Review"... recommended for specialists in the theoretical or biophysical fields ..." * Angewandte Chemie, International Edition, 2003, Vol 42, No 45, 24 November 2003, p 5541 *
"... informative and stimulating." * Chemistry & Industry, Issue 25, 15 December 2003, p 21 *
Table of ContentsI. Probing Biological Molecules: Theory and Experiment; Flow Oriented Linear Dichroism to Probe Protein Orientation in Membrane Environments; Quantitative Protein Circular Dichroism Calculations; Probing Cellular Structure and Function by Atomic Force Microscopy; Physical Characterization of Wild Type and mnn9 Mutant Cells of Saccharomyces cerevisiae by Atomic Force Microscopy (AFM); Probing Supramolecular Organisation at Immune Synapses; Probing the Structure of Viral Ion Channel Proteins: A Computational Approach; The Impact of H2O2 on the Structure of Catalases by Molecular Modelling Methods; Entropy in the Alignment and Dimerization of Class C G-Protein Coupled Receptors; Electrostatic Stability of Wild Type and Mutant Transthyretin Oligomers; Simulations of Human Lysozyme: Conformations Triggering Amyloidosis in 156T Mutant; Collective Excitation Dynamics in Molecular Aggregates: Exciton Relaxation, Self-Trapping and Polaron Formation; Surprising Electro-Magnetic Properties of Close Packed Organized Organic Layers - Magnetization of Chiral Monolayers of Polypeptide; Barrier Crossing by a Flexible Long Chain Molecule - The Kink Mechanism; II. Proteins, Lipids and their Interactions; Lipid Interaction with Cytidylyltransferase Regulates Membrane Synthesis; Models and Measurements on the Monolayer Bending Energy of Inverse Lyotropic Mesophases; Hemolytic and Antibacterial Activities of LK Peptides of Various Topologies: A Monolayer and PM-IRRAS Approach; A Novel Approach for Probing Protein-Lipid Interactions of MscL, a Membrane-Tension-Gated Channel; Folding of the α-Helical Membrane Proteins DsbB and NhaA; FhuA, an Escherichia coli Transporter and Phage Receptor; Morphological Aspects of In Cubo Protein Crystallisation; Mobility of Proteins and Lipids in the Photosynthetic Membranes of Cyanobacteria; Partitioning and Thermodynamics of Chlordiazepoxide in n-Octanol/Buffer and Liposome System; Distribution of Vitamin E In Model Membranes; Theory on Opening-Up of Liposomal Membranes by Adsorption of Talin; Differential Scanning Calorimetry and X-Ray Diffraction Studies of Glycolipid Membranes; Subject Index.
