Description
Book Synopsisan impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focusâ. the ample problems and tutorials throughout are much appreciated.
âTobin R. Sosnick, Professor and Chair of Biochemistry and Molecular Biology, University of Chicago
Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual, intuitive, and rigorous. This approach will greatly benefit students at all levels.
âVijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University
a masterful tour de forceâ. Barrick's rigor and scholarship come through in every chapter.
âRohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis
This book provides a comprehensive, contemporary introduction to developing a quantitative understanding of how biological macromolecules beh
Trade Review
"Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual, intuitive, and rigorous. This approach will greatly benefit students at all levels."
–Vijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University
"a masterful tour de force…. Barrick's rigor and scholarship come through in every chapter. The focus on biomolecules combined with the detailed demonstrations of how concepts apply to practical aspects of biophysics make this a truly unique contribution. Everyone, from the purported expert to the true novice will gain immensely from this carefully crafted, well motivated, and deeply thought out contribution. This book should live on all of our bookshelves and be consulted routinely as a quick reference or as material for in depth study and training."
—Rohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis
"The author has created an impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focus. It starts by bringing students up to speed on probability theory, multi-variate calculus and data fitting, the necessary tools for tackling the advanced topics covered in the remaining dozen chapters and for conducting rigorous interdisciplinary research…. the ample problems and tutorials throughout are much appreciated."
—Tobin R. Sosnick, Professor and Chair, Dept of Biochemistry and Molecular Biology, University of Chicago
"Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual, intuitive, and rigorous. This approach will greatly benefit students at all levels."
–Vijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University
"a masterful tour de force…. Barrick's rigor and scholarship come through in every chapter. The focus on biomolecules combined with the detailed demonstrations of how concepts apply to practical aspects of biophysics make this a truly unique contribution. Everyone, from the purported expert to the true novice will gain immensely from this carefully crafted, well motivated, and deeply thought out contribution. This book should live on all of our bookshelves and be consulted routinely as a quick reference or as material for in depth study and training."
—Rohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis
"The author has created an impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focus. It starts by bringing students up to speed on probability theory, multi-variate calculus and data fitting, the necessary tools for tackling the advanced topics covered in the remaining dozen chapters and for conducting rigorous interdisciplinary research…. the ample problems and tutorials throughout are much appreciated."
—Tobin R. Sosnick, Professor and Chair, Dept of Biochemistry and Molecular Biology, University of Chicago
Table of ContentsSeries Preface
Preface
Acknowledgments
Note to Instructors
Author
Chapter 1 Probabilities and Statistics in Chemical and Biothermodynamics
Chapter 2 Mathematical Tools in Thermodynamics
Chapter 3 The Framework of Thermodynamics and the First Law
Chapter 4 The Second Law and Entropy
Chapter 5 Free Energy as a Potential for the Laboratory and for Biology
Chapter 6 Using Chemical Potentials to Describe Phase Transitions
Chapter 7 The Concentration Dependence of Chemical Potential, Mixing, and Reactions
Chapter 8 Conformational Equilibrium
Chapter 9 Statistical Thermodynamics and the Ensemble Method
Chapter 10 Ensembles That Interact with Their Surroundings
Chapter 11 Partition Functions for Single Molecules and Chemical Reactions
Chapter 12 The Helix–Coil Transition
Chapter 13 Ligand Binding Equilibria from a Macroscopic Perspective
Chapter 14 Ligand Binding Equilibria from a Microscopic Perspective
Appendix: How to Use Mathematica 485
Bibliography
Index
